Results 1 to 10 of about 151,591 (120)
Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]
PLoS ONE, 2011 In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi +4 more
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Weight Change Alters the Small RNA Profile of Urinary Extracellular Vesicles in Obesity
Obesity Facts, 2022 Introduction: Various kidney diseases reportedly show different urinary extracellular vesicle (EV) RNA profiles. Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA in obesity is uncertain.
Dughyun Choi +12 more
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Cell Reports, 2020 Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov +10 more
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PLoS Neglected Tropical Diseases, 2022 The parasite Trypanosoma brucei grows as bloodstream forms in mammalian hosts, and as procyclic forms in tsetse flies. In trypanosomes, gene expression regulation depends heavily on post-transcriptional mechanisms.
Tania Bishola Tshitenge +3 more
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Investigation of Novel RNA Elements in the 3′UTR of Tobacco Necrosis Virus-D
Viruses, 2020 RNA elements in the untranslated regions of plus-strand RNA viruses can control a variety of viral processes including translation, replication, packaging, and subgenomic mRNA production.
Laura R. Newburn +2 more
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Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response
Nature Communications, 2023 Long noncoding RNA molecules are RNA transcripts long thought to remain untranslated. In this study, the authors demonstrate that certain lncRNA can be translated into peptides that are immunogenic to CD8+ T cells and promote anti-tumour responses when ...
Wojciech Barczak +11 more
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The RNA Architecture of the SARS-CoV-2 3′-Untranslated Region
Viruses, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3′ untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication ...
Junxing Zhao +4 more
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Novel positive-sense, single-stranded RNA (+ssRNA) virus with di-cistronic genome from intestinal content of freshwater carp (Cyprinus carpio). [PDF]
PLoS ONE, 2011 A novel positive-sense, single-stranded RNA (+ssRNA) virus (Halastavi árva RNA virus, HalV; JN000306) with di-cistronic genome organization was serendipitously identified in intestinal contents of freshwater carps (Cyprinus carpio) fished by line-fishing
Ákos Boros +3 more
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circSnx12 Is Involved in Ferroptosis During Heart Failure by Targeting miR-224-5p
Frontiers in Cardiovascular Medicine, 2021 Circular RNA (circRNA) is a subclass of non-coding RNAs that enables the circular transcripts resistant to the exonuclease digestion. Iron homeostasis is essential for the body to maintain normal physiological functions.
Haoyuan Zheng +7 more
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Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]
PLoS Genetics, 2010 The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng +8 more
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