Results 1 to 10 of about 152,090 (265)
The RNA Architecture of the SARS-CoV-2 3′-Untranslated Region [PDF]
Viruses, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3′ untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication ...
Junxing Zhao +4 more
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Aberrant Regulation of Messenger RNA 3′-Untranslated Region in Human Cancer
Cellular Oncology, 2007 The messenger RNA 3′-untranslated region (3′UTR) is emerging as critically important in regulating gene expression at posttranscriptional levels. The 3′UTR governs gene expression via orchestrated interactions between mRNA structural components (cis ...
Isabel López de Silanes +2 more
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The untranslated regions of classic swine fever virus RNA trigger apoptosis.
PLoS ONE, 2014 Classical swine fever virus (CSFV) causes a broad range of disease in pigs, from acute symptoms including high fever and hemorrhages, to chronic disease or unapparent infection, depending on the virus strain.
Wei-Li Hsu +7 more
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Role of noncoding RNAs and untranslated regions in cancer: A review
Medicine, 2022 Cancer is one of the most prevalent diseases worldwide, and poses a threat to human health. Noncoding RNAs (ncRNAs) constitute most transcripts, but they cannot be translated into proteins. Studies have shown that ncRNAs can act as tumor suppressors or oncogenes.
Yiping Zhang +3 more
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Hfq Is Necessary for Regulation by the Untranslated RNA DsrA [PDF]
Journal of Bacteriology, 2001 ABSTRACTDsrA is an 85-nucleotide, untranslated RNA that has multiple regulatory activities at 30°C. These activities include the translational regulation of RpoS and H-NS, global transcriptional regulators inEscherichia coli. Hfq is anE. coliprotein necessary for the in vitro and in vivo replication of the RNA phage Qβ.
D D, Sledjeski, C, Whitman, A, Zhang
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Expression of distinct RNAs from 3′ untranslated regions [PDF]
Nucleic Acids Research, 2010 The 3' untranslated regions (3'UTRs) of eukaryotic genes regulate mRNA stability, localization and translation. Here, we present evidence that large numbers of 3'UTRs in human, mouse and fly are also expressed separately from the associated protein-coding sequences to which they are normally linked, likely by post-transcriptional cleavage.
T. Mercer +12 more
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Untranslated Regions of a Mobile Transcript Mediate RNA Metabolism [PDF]
Plant Physiology, 2009 BEL1-like transcription factors are ubiquitous in plants and interact with KNOTTED1 types to regulate numerous developmental processes. In potato (Solanum tuberosum subsp. andigena), the BEL1-like transcription factor StBEL5 and its Knox protein partner regulate tuber formation by targeting genes that control growth.
Banerjee, Anjan K. +2 more
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Small Untranslated RNA Antitoxin inBacillus subtilis [PDF]
Journal of Bacteriology, 2005 ABSTRACTToxin-antitoxin (TA) modules are pairs of genes in which one member encodes a toxin that is neutralized or whose synthesis is prevented by the action of the product of the second gene, an antitoxin, which is either protein or RNA. We now report the identification of a TA module in the chromosome ofBacillus subtilisin which the antitoxin is an ...
Jessica M, Silvaggi +2 more
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Circular RNAs and Untranslated Regions in Acute Myeloid Leukemia
International Journal of Molecular Sciences, 2023 Before the advent of next-generation sequencing, research on acute myeloid leukemia (AML) mostly centered on protein-coding genes. In recent years, breakthroughs in RNA sequencing technologies and whole transcriptome analysis have led to the discovery that approximately 97.5% of the human genome is transcribed into non-coding RNAs (ncRNAs).
Yeh, Shih-Chia +2 more
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Structure of the 5′ Untranslated Region of Enteroviral Genomic RNA [PDF]
Journal of Virology, 2019 Enterovirus infections are responsible for human diseases, including myocarditis, pancreatitis, acute flaccid paralysis, and poliomyelitis. The virulence of these viruses depends on efficient recognition of the RNA genome by a large family of host proteins and protein synthesis factors, which in turn relies on the three-dimensional folding of the first
Mahmud, Bejan +2 more
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