Results 51 to 60 of about 787 (112)

The Two Faces of Angiopoietin‐Like Protein 2 in Cancer

Cancer Science, Volume 116, Issue 3, Page 592-599, March 2025.
In this Review, Horiguchi et al. focus on ANGPTL2 activity in the tumor microenvironment and its function in anti‐cancer immunity. ABSTRACT The tumor microenvironment is composed of tumor cells and various stromal cell types, such as immune cells, fibroblasts, and vascular cells.
Haruki Horiguchi, Tsuyoshi Kadomatsu, Yuichi Oike   +2 more
wiley   +1 more source

Cytomorphology and clinicopathologic correlation of TFE3‐rearranged renal cell carcinoma

Cancer Cytopathology, Volume 133, Issue 2, February 2025.
Abstract Background TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) harbors gene fusions involving TFE3 with one of many different partner genes. Because of their diverse morphologies, the differential diagnosis is broad and challenging. Publications focusing on the cytomorphology of TFE3‐rRCC are sparse.
Tieying Hou, Xiaoqi Lin
wiley   +1 more source

Concomitant presentation and surgical management of an abdominal aortic aneurysm and translocation XP11.2 associated renal cell carcinoma in a female infant

Journal of Pediatric Surgery Case Reports, 2018
Abdominal Aortic Aneurysms are rare in the infant population, when these occur are secondary to connective tissue diseases, vasculitis, and infectious etiology or in relation with tuberous sclerosis.
Ramón Garcia–Alva, Javier E. Anaya-Ayala, Gabriel Lopez-Pena, Lizeth Luna, Cesar Cuen-Ojeda, Rene Lizola, Eduardo Lopez-Corella, Carlos A. Hinojosa   +7 more
doaj   +1 more source

TFE3‐rearranged nonmelanotic renal PEComa: a case series expanding their phenotypic and fusion landscape

Histopathology, Volume 85, Issue 5, Page 783-793, November 2024.
TFE3‐rearranged renal PEComas display high cytomorphological diversity with clear, eosinophilic, or mixed cell types, but lack significant anaplasia and pleomorphism. Their phenotypic diversity is paralleled by the diversity of their TFE3 gene fusion partner landscape. Homogeneous and strong TFE3 expression is characteristic.
Abbas Agaimy, Andres M Acosta, Liang Cheng, Katrina Collins, Eddie Fridman, Christoph Schubart, Sean R Williamson, Arndt Hartmann, Kiril Trpkov   +8 more
wiley   +1 more source

A nomogram based on TFE3 IHC results and clinical factors as a preliminary screening scheme for TFE3‐rearranged renal cell carcinoma

Cancer Medicine, Volume 13, Issue 5, March 2024.
Abstract Background TFE3 immunohistochemistry (TFE3‐IHC) is controversial in the diagnosis of TFE3‐rearranged renal cell carcinoma (TFE3‐rearranged RCC). This study is to investigate the accuracy and sensitivity of IHC and establish a predictive model to diagnose TFE3‐rearranged RCC.
Pengju Li, Quanhui Xu, Minyu Chen, Jiangquan Zhu, Yinghan Wang, Mukhtar A. Mumin, Kangbo Huang, Zeying Jiang, Hui Liang, Qiong Deng, Zhu Wang, Bing Liao, Wenfang Chen, Yun Cao, Jiazheng Cao, Junhang Luo   +15 more
wiley   +1 more source

Targeted therapies in children with renal cell carcinoma (RCC): An International Society of Pediatric Oncology—Renal Tumor Study Group (SIOP‐RTSG)‐related retrospective descriptive study

Cancer Medicine, Volume 13, Issue 1, January 2024.
This is the first SIOP‐RTSG retrospective study that reports response‐ and survival data of pediatric patients with renal cell carcinoma (RCC) who were treated with targeted therapy. Thirty‐one patients with advanced‐stage RCC were treated with 17 different treatment regimens, highlighting current treatment heterogeneity.
Julia Sprokkerieft, Justine N. van der Beek, Filippo Spreafico, Barbara Selle, Estelle Thebaud, Tanzina Chowdhury, Jesper Brok, Gábor Ottóffy, Xiaofei Sun, Gema L. Ramírez Villar, Garik Sagoyan, Heidi Segers, Dimitrios Doganis, Annalisa Serra, Lauriane Lemelle, Norbert Graf, Arnauld C. Verschuur, Godelieve A. M. Tytgat, Marry M. van den Heuvel‐Eibrink   +18 more
wiley   +1 more source

The Relevance of the Virchow Node and Virchow Triad in Renal Cancer Diagnosis

Clinics and Practice
Background: The purpose of this article is to overview the clinical significance of left supraclavicular adenopathy and review the etiology of inferior vena cava (IVC) thrombosis, starting from a presentation of a rare case of renal cell carcinoma (RCCs)
Luiza-Roxana Dorobantu-Lungu, Viviana Dinca, Andrei Gegiu, Dan Spataru, Andreea Toma, Luminita Welt, Mihaela Florentina Badea, Constantin Caruntu, Cristian Scheau, Ilinca Savulescu-Fiedler   +9 more
doaj   +1 more source

Kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion

International Brazilian Journal of Urology, 2005
We report the case of a 58-year old patient, showing a solid image in the right kidney, who underwent radical nephrectomy that revealed neoplasia, whose pathological study led to the diagnosis of kidney carcinoma associated with Xp11.2 translocation ...
Paulo G. O. Salles, Mario Soto Jr
doaj   +1 more source

Xp11 Translocation Renal Cell Carcinoma: Unusual Variant Masquerading as Upper Tract Urothelial Cell Carcinoma

Urology Case Reports, 2014
Xp11 translocation renal cell carcinoma (TRCC) is a rare subtype of renal cell carcinoma characterized by chromosomal translocations involving the TFE3 gene located at the Xp11.2 locus.
Arash Akhavein, Julia Han, Christopher Carter, Samer Z. Al-Quran, Li-Ming Su   +4 more
doaj   +1 more source

Xp11.2 Translocation Renal Cell Carcinoma: A Rare Renal Cell Carcinoma. [PDF]

Cureus, 2023
Kalita P, Dey B, Saurabh A, Chishti SF.
europepmc   +1 more source