Difference in response reliability predicted by STRFs in the cochlear nuclei of barn owls [PDF]
The brainstem auditory pathway is obligatory for all aural information. Brainstem auditory neurons must encode the level and timing of sounds, as well as their time-dependent spectral properties, the fine structure and envelope, which are essential for ...
Jose L. Pena, Louisa J. Steinberg
core +3 more sources
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
A general fabricating strategy for arbitrary 3D organic mixed ionic‐electronic conductor architectures is reported using PEDOT:PSS microfiber building blocks. A water‐assisted self‐fusion process is successfully developed in which adhesion can be modulated as reversible (PSS‐rich) or irreversible (PEDOT‐rich) self‐fusion depending on the post‐treatment
Youngseok Kim +8 more
wiley +1 more source
IL-1R and inflammasomes mediate early pulmonary protective mechanisms in respiratory brucella abortus infection [PDF]
Brucella spp. infection is frequently acquired through contaminated aerosols. The role of interleukin-1 beta (IL-1β) in the early pulmonary response to respiratory Brucella infection is unknown.
Alonso Paiva, Iván Mathias +9 more
core +1 more source
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl +27 more
wiley +1 more source
Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy [PDF]
Dynamic visualization of the intravascular events leading to the extravasation of leukocytes into tissues by intravital microscopy has significantly expanded our understanding of the underlying molecular processes.
Hutter, J. +4 more
core +1 more source
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu +13 more
wiley +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Comparison of Xylazine, Lidocaine, Xylazine-Lidocaine Lumbosacral Epidural on Analgesia and Cardiopulmonary Functions in Sedated West African Dwarf Goats [PDF]
Ruminants are commonly subjected to loco-regional anaesthetic techniques over general anaesthesia due to minimal side effects. There is still limited information on the effects of some drug protocols in use.
Foluso Bolaji-Alabi, Oladotun Awoyemi
doaj +1 more source
Pigmented melanoma cell migration study on murine syngeneic B16F10 melanoma cells or tissue transplantation models [PDF]
Melanoma is a lethal form of skin cancer with poor prognosis, especially due to the early metastatic feature. Recent studies have shown that the melanin pigment influences the nanomechanical properties and, therefore, the metastatic behavior of the ...
Buteică, Sandra Alice +5 more
core +2 more sources

