Results 111 to 120 of about 150,572 (297)

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

Epilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire, Elise Collard, Abigail Niyibizi, Natasha N. Kumar, Enrique Germany Morrison, Javier Chavez Cerda, Ayse S. Dereli, Riem El Tahry   +7 more
wiley   +1 more source

“Anything can happen”: experiences of people using opioids in a xylazine market

Harm Reduction Journal
Background Xylazine is associated with a number of negative health outcomes, such as severe wounds and withdrawal. As xylazine increasingly emerges in drug markets across the United States, there is an urgent need for a national response to reduce ...
Megan K. Reed, Karla Martin González, Traci C. Green, Tracy Esteves Camacho, Rose Laurano, Frida Clark-García, Catalyst Geraci, Ava Kane, Kristin L. Rising   +8 more
doaj   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Providers’ knowledge and perception of xylazine in the unregulated drug supply: a sequential explanatory mixed-methods study

Harm Reduction Journal
Background Xylazine is increasingly prevalent in the unregulated opioid supply in the United States. Exposure to this adulterant can lead to significant harm, including prolonged sedation and necrotic wounds.
Katherine Hill, Rebecca Minahan-Rowley, Emma T. Biegacki, Robert Heimer, Kimberly L. Sue   +4 more
doaj   +1 more source

Large-scale changes in cortical dynamics triggered by repetitive somatosensory electrical stimulation. [PDF]

, 2019
BackgroundRepetitive somatosensory electrical stimulation (SES) of forelimb peripheral nerves is a promising therapy; studies have shown that SES can improve motor function in stroke subjects with chronic deficits.
Burish, Mark J, Ganguly, Karunesh, Gulati, Tanuj, Hishinuma, April K   +3 more
core   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Influence of commonly used pharmaceutical agents on equine bone marrow-derived mesenchymal stem cell viability [PDF]

, 2017
Ankrum, Becerra, Bohannon, Broeckx, Chang, Distelhorst, Donega, Dregalla, Ferris, Fredriksson, Frisbie, Garcia-Villar, Garvican, Godwin, Guest, Guest, Hammer, Keegan, McIlwraith, Müller, Nagy, Parker, Qiu, Salonen, Smith, Smith, Sole, Sole, Strober, Tan, Wilke, Wyles, Zhang   +32 more
core   +2 more sources

Superparamagnetic iron oxide polyacrylic acid coated {\gamma}-Fe2O3 nanoparticles does not affect kidney function but causes acute effect on the cardiovascular function in healthy mice

, 2012
This study describes the distribution of intravenously injected polyacrylic acid (PAA) coated {\gamma}-Fe2O3 NPs (10 mg kg-1) at the organ, cellular and subcellular levels in healthy BALB/cJ mice and in parallel addresses the effects of NP injection on ...
Baatrup, Erik, Berret, Jean-Francois, Bie, Peter, Fresnais, Jérome, Frische, Sebastian, Hansen, Pernille B. L., Iversen, Nina K., Laustsen, Christoffer, Pedersen, Michael, Thomsen, Karen, Wang, Tobias   +10 more
core   +3 more sources

Brief report: Meth, tranq, gas station heroin & other drugs complicating addiction treatment. [PDF]

Am J Addict
Abstract Background and Objectives Patients using fentanyl have worse treatment outcomes; however, little is known about other drugs that complicate treatment. Methods A national survey (n = 396) was conducted using a random sample of clinicians waivered to prescribe buprenorphine in the United States.
Winstanley EL, Liebschutz JM, Murray-Krezan C, Switzer GE, Nash S, Kawasaki S.   +5 more
europepmc   +2 more sources

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source