Results 141 to 150 of about 157,061 (320)

Vocal Fold Scar Treatment via Controlled Dexamethasone Delivery With a Light‐Activatable Implant

The Laryngoscope, EarlyView.
A light‐activatable dexamethasone implant was employed for the treatment of vocal fold (VF) scarring in a rabbit model. The implant enables controlled, repeatable drug release via near‐infrared laser irradiation, improving biomechanics, vibratory function, and histological architecture at the injury site.
Denzel Ryan D. Cruz, Nour Awad, Avery Zheng, Alexander Karabachev, Charles Farbos de Luzan, Yoonjee C. Park, Gregory R. Dion   +6 more
wiley   +1 more source

Synergism of the analgesic activities of tramadol with α2 adrenoreceptor agonist xylazine in mice [PDF]

Iraqi Journal of Veterinary Sciences, 2012
The present study was undertaken to evaluate the antinociceptive interaction between tramadol and xylazine. The antinociceptive effect of intraperitoneal (I.P) administration of the drug alone or in combination was evaluated using the mouse hot-plate ...
G. A. Taqa
doaj  

Dynamic Retinal Pathology in Glaucoma Progression Revealed by High‐Resolution Functional Imaging in Vivo

Laser &Photonics Reviews, EarlyView.
In this work, we investigated the dynamic retinal pathology of glaucoma from onset to late stages through longitudinal in vivo high‐resolution imaging in a silicone oil‐induced ocular hypertension (SOHU) glaucoma mouse model. We developed an optimized adaptive optics two‐photon excitation fluorescence microscopy (AO‐TPEFM) technique for morphological ...
Yiming Fu, Pham Binh Minh, Sicong He, Yingzhu He, Zhongya Qin, Ting Xie, Jianan Qu   +6 more
wiley   +1 more source

Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms. [PDF]

, 2015
Cardiac dysfunction is a prominent cause of mortality in myotonic dystrophy I (DM1), a disease where expanded CUG repeats bind and disable the muscleblind-like family of splice regulators.
Choi, Jongkyu, Comai, Lucio, Dixon, Donald M, El-Ghazali, Ayea, Fishbein, Michael C, Jordan, Maria C, Park, Sun Young, Reddy, Sita, Roos, Kenneth P   +8 more
core  

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

Pediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan, Samuel M. Lee, Ali Imran Sarwar, Yuxing Yuan, Sunny Chen, Maricela Castellon, Dan A. Marian, Richard D. Minshall, Jie Tian, Irena Levitan, Jiwang Chen   +10 more
wiley   +1 more source

Crosslinked Gelatin‐Polycaprolactone Scaffolds: Balancing Biocompatibility and Inflammatory Response for Tissue Engineering Applications

Polymer Engineering &Science, EarlyView.
Crosslinked gelatin‐functionalized PCL scaffolds exhibited enhanced hydrophilicity, structural stability, and porous interactions. In vitro assays demonstrated improved osteoblast adhesion, viability, and proliferation without cytotoxicity, while in vivo evaluation showed no adverse inflammatory response, supporting their potential application in ...
Fernanda Ramírez‐Ruiz, Israel Núñez‐Tapia, Lucía Pérez‐Sánchez, María Cristina Piña‐Barba, Irving Sanchez‐Leal, Marco Antonio Alvarez‐Perez, Iriczalli Cruz‐Maya, Janeth Serrano‐Bello   +7 more
wiley   +1 more source

Xylazine-induced skin lesions: clinical presentation and management perspectives on an emerging drug epidemic

Academia Medicine
Xylazine, a veterinary sedative, has emerged as a significant adulterant in the illicit drug supply, particularly in opioids. Its prevalence has risen dramatically, with detection rates reaching 80% in some areas of the Northeastern United ...
Kritin K. Verma, Jonathan Tipo, Brenna Bunch, Daniel P. Friedmann, Michelle B. Tarbox   +4 more
doaj   +1 more source

Plexus brachialis block as part of balanced analgesia in a sheep undergoing arthrodesis of the carpus [PDF]

, 2019
Michielsen, Anneleen, Schauvliege, Stijn
core   +2 more sources

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

Small, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu, Mark Louis P. Vidallon, Yuyang Song, Aidan P. G. Walsh, Henry Gordon, Shulei Ren, Pengkai Shi, Bangyan Xu, Mitchell J. Moon, Sylvain Trépout, Rico F. Tabor, Alexis I. Bishop, Ulrich Flögel, Karlheinz Peter, Xiaowei Wang   +14 more
wiley   +1 more source

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions

Veterinary Record, EarlyView.
Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö, Lovisa Snygg, Maja Wiklund, Görel Nyman   +3 more
wiley   +1 more source