Results 231 to 240 of about 157,061 (320)

Evaluation of sedation for standing clinical procedures in horses using detomidine combined with buprenorphine [PDF]

open access: yes
Alan Taylor   +31 more
core   +1 more source

Ageing reveals the latent effects of early life stress on respiratory and metabolic function in female rats: Novel insights into the sex‐specific origins of sleep apnoea

open access: yesExperimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is ∼2 times more prevalent in men than women. However, this changes at menopause as the occurrence of SA increases and matches that of men. Menopause is a natural process, but it remains unclear why SA emerges only in a subpopulation of ageing women.
Danuzia Ambrozio‐Marques   +4 more
wiley   +1 more source

Fmr1 knockout disrupts multiple intrinsic properties via reduced HCN channel activity in mediodorsal thalamocortical neurons

open access: yesExperimental Physiology, EarlyView.
Abstract The neurodevelopmental disorder fragile X syndrome (FXS) results from hypermethylation of the FMR1 gene, which prevents production of the FMRP protein. FMRP modulates the expression and function of a variety of proteins, including voltage‐gated ion channels, such as hyperpolarization‐activated and cyclic nucleotide‐gated (HCN) channels, which ...
Gregory J. Ordemann   +3 more
wiley   +1 more source

The effects of e‐cigarette use on asthma severity in adult BALB/c mice

open access: yesExperimental Physiology, EarlyView.
Abstract Electronic cigarettes (e‐cigarettes) are often perceived to be a less harmful alternative to tobacco cigarettes. Potentially due to this perception, they are used by people with pre‐existing respiratory conditions, such as asthma, who otherwise would not smoke. Despite this, there are few studies exploring the health effects of e‐cigarette use
Jenield J. D'abreo   +9 more
wiley   +1 more source

Optimising exercise intensity for gut health: Effect on microbiota composition, barrier integrity and inflammation in male Wistar rats

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise influences gut microbiota composition and intestinal permeability, but the optimal intensity for maintaining gut health remains unclear. This study investigates the effects of different exercise intensities on abundance of some gut microbiota, epithelial barrier integrity and inflammatory markers.
Nova Sylviana   +3 more
wiley   +1 more source

Impact of combined ginsenoside‐MC1 and irisin on mitochondrial apoptosis in diabetic rats with hepatic reperfusion injury: Role of AMPK/JNK signalling

open access: yesExperimental Physiology, EarlyView.
Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin   +4 more
wiley   +1 more source

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