Results 61 to 70 of about 110,075 (237)

Philadelphia Consensus on the Surgical Management of Xylazine-Associated Wounds in People Who Use Drugs

SurgiColl
Xylazine-related wounds are increasingly presenting an addiction medicine and surgical dilemma in people who use drugs. Initially developed as a veterinary sedative, xylazine has been found increasingly added to illicitly manufactured fentanyl ...
Asif M. Ilyas, Sina Ramtin, Erum N. Ilyas, Mark K. Solarz, Andrew Miller, Lisa Rae, Jason Wink, Rachel Haroz, Lara Weinstein, Katharine T. Criner-Woozley   +9 more
doaj   +1 more source

Effects of oropharyngeal neuromuscular stimulation on the volumetric enlarged and reduced tongue base in minipigs

The Anatomical Record, EarlyView.
Abstract Hypoglossal nerve or tongue protruding muscle stimulation is a current treatment option for obstructive sleep apnea. Thus, the present study analyzed 3D deformations of the volumetric enlarged and reduced tongue base upon oropharyngeal neuromuscular stimulation.
Sydney Chen, Doris Haydee Rosero Salazar, Zi‐Jun Liu   +2 more
wiley   +1 more source

Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico

Harm Reduction Journal
Background Xylazine is a α2-adrenergic receptor agonist, used for sedation in veterinary contexts. Although it is increasingly found in overdose deaths across North America, the clinical management of xylazine-involved overdoses has not been extensively ...
Lilia Pacheco Bufanda, Alejando González Montoya, Brenda Torres Carrillo, Mariana Alejandra Gonzalez Tejeda, Luis A. Segovia, Alhelí Calderón-Villarreal, Joseph R. Friedman   +6 more
doaj   +1 more source

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy (Kerodon rupestris) and the common marmoset (Callithrix jacchus)

The Anatomical Record, EarlyView.
Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso, Yasmin Pinto Fernandes Albuquerque, Karina Maia Paiva, Rodrigo Freire Oliveira, Nelyane Nayara Martins de Santana, Expedito Silva do Nascimento‐Júnior, Rovena Clara G. J. Engelberth, Jeferson de Souza Cavalcante, Adhil Bhagwandin, Paulo Leonardo Araújo de Góis Morais, José Rodolfo Lopes de Paiva Cavalcanti   +10 more
wiley   +1 more source

EFFECT OF XYLAZINE ON SOME ENDOCRINOLOGICAL AND HAEMATOLOGICAL PARAMETERS IN HEIFERS UNDER THERMONEUTRAL OR HEAT STRESS CONDITIONS [PDF]

Veterinary Medical Journal - Giza
A study was performed to assess the effect of xylazine HCI (0.1 mg/kg of body weight, IV) in heifers maintained at thermoneutral (TN; 18°C, 42% RH) or heat stress (HS;33°C, 63% RH) conditions.
ABDALLA B., FAYED H.
doaj   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

BMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai, Yifu Tan, Jiaheng Liang, Shen Liu, Jiabin Zhao, Shanbo Ma, Chunxin Liu, Minghua Du, Mark Selvan, Xiaopeng Shi, Liqiang Song, Peng Li   +11 more
wiley   +1 more source

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober, Michael A. Stellon, Matt A. Culver, Amy Frenkel, Dana Irrer, Colleen M. Witzenburg, Alejandro Roldán‐Alzate, Luke Lamers   +7 more
wiley   +1 more source

Unmasking a neurotoxic duo: a comprehensive overview of fentanyl–xylazine crosstalk in kinase pathways

Frontiers in Cellular Neuroscience
IntroductionFentanyl is the main cause of the US overdose crisis, responsible for over half of overdose deaths, totaling around 75,000 lives each year. The contamination of the illegal drug supply with xylazine has been linked to an increase in overdose ...
Sally N. Pauss, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr, Terry D. Hinds Jr, Terry D. Hinds Jr   +5 more
doaj   +1 more source

Comparison of Xylazine, Lidocaine, Xylazine-Lidocaine Lumbosacral Epidural on Analgesia and Cardiopulmonary Functions in Sedated West African Dwarf Goats [PDF]

Iranian Journal of Veterinary Surgery
Ruminants are commonly subjected to loco-regional anaesthetic techniques over general anaesthesia due to minimal side effects. There is still limited information on the effects of some drug protocols in use.
Foluso Bolaji-Alabi, Oladotun Awoyemi
doaj   +1 more source

Detection of Nitazenes in the Illicit Drug Supply Utilizing Precursor Ion Scan Methods With Paper Spray Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin, Irene Shkolnikov, Jindar Sboto, Collin Kielty, Bruce Wallace, Chris G. Gill, Dennis K. Hore   +6 more
wiley   +1 more source