Results 41 to 50 of about 9,122 (295)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Morphology and anatomic-surgical segmentation of the spleen of Pecari tajacu Linnaeus, 1758
Bioscience Journal, 2018 The spleen is a secondary lymphoid organ with importance in clinical surgery. Due this and the lack of data in the literature, the current paper analyzes the organ´s morphology and segmentation in collared peccaries.
Gleidson Benevides de Oliveira +8 more
doaj +3 more sources
Journal of Applied Oral Science, 2010 OBJECTIVES: The aim of this study was to test the efficacy of a locally applied 8.5% nanostructured doxycycline (DOX) gel in preventing alveolar bone loss in experimental periodontal disease (EPD) in rats by using the tapping mode atomic force microscopy
Marco Antonio Botelho +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Histology of ovine placenta during gestation periods
Kufa Journal for Veterinary Medical Sciences, 2011 Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the
A. F. Majeed +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Brazilian Oral ResearchThis study evaluated the removal of filling material with ProTaper Universal Rotary Retreatment system (PTR) combined with solvents and the influence of solvents on the bond strength (PBS) of sealer to intraradicular dentin after canal reobturation ...
Marcelo PALHAIS +6 more
doaj +1 more source
Histology of ovine placenta during gestation periods
Kufa Journal for Veterinary Medical Sciences, 2012 Placetomes were collected from 93 pregnant slaughtered Ewes at different gestation periods , from AL.Falluja slaughter house during the periods from 2, Jully 2009 to 30, December ,2010 . Tissue specimens for microscopic examination were taken from the
M. S. Shalal +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source