Results 211 to 220 of about 148,176 (359)

Structural and functional insights into extreme thermal stability and activity of two GH12 domains of a multidomain glycosidase from a hyperthermophilic euryarchaeon

open access: yesThe FEBS Journal, EarlyView.
The multidomain glycosidase MDG from the hyperthermophilic euryarchaeon Thermococcus sp. contains five protein domains: three catalytic domains (GH5, GH12‐1, and GH12‐2) and two cellulose‐binding modules (CBM2). In this study, the GH12‐1 and GH12‐2 domains were individually purified and biochemically characterized.
Kseniya S. Zayulina   +11 more
wiley   +1 more source

Genomic context analysis enables the discovery of an unusual NAD‐dependent racemase in phosphonate catabolism

open access: yesThe FEBS Journal, EarlyView.
The authors identify PbfF (previously annotated as a NAD‐dependent dehydrogenase) as a hitherto unknown enzyme in phosphonate catabolism. Guided by genome context analysis, they show that PbfF is actually a racemase, serving to degrade the natural compound (S)‐2‐amino‐1‐hydroxyethylphosphonate (S‐HAEP).
Francesca Ruffolo   +8 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

FlhG Cooperates With the Cell Cycle Regulator GpsB to Confine Peritrichous Flagella in B. subtilis

open access: yesMolecular Microbiology, EarlyView.
FlhG (orange, with activator helix in green) regulates peritrichous flagellation in Bacillus subtilis by interacting with the C‐ring protein FliY (gray, N‐terminus in red) and the cell wall regulator GpsB (N‐terminus in blue, C‐terminus in red). GpsB recruits PBP1 for peptidoglycan synthesis, linking flagellar assembly to cell wall biosynthesis.
Anita Dornes   +6 more
wiley   +1 more source

The role of VND transcription factors in xylem vessel development and secondary wall formation

open access: yesNew Phytologist, EarlyView.
Summary Transitioning from aquatic to terrestrial life required specialized vascular tissues, with xylem enabling water transport and structural support. Vascular‐related NAC (NAM, ATAF1/2, CUC2) domain (VND) transcription factors regulate xylem development by orchestrating secondary cell wall biosynthesis and programmed cell death.
Ulrike Lehmann, René Schneider
wiley   +1 more source

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