Novel xylose transporter Cs4130 expands the sugar uptake repertoire in recombinant Saccharomyces cerevisiae strains at high xylose concentrations [PDF]
Biotechnology for Biofuels, 2020 Background The need to restructure the world’s energy matrix based on fossil fuels and mitigate greenhouse gas emissions stimulated the development of new biobased technologies for renewable energy.
João Gabriel Ribeiro Bueno +8 more
doaj +8 more sources
Resurrection and characterization of ancestral xylose transporters enhance the capability of xylose uptake in the mixed sugar co-fermentation of Recombinant Saccharomyces cerevisiae [PDF]
Bioresources and BioprocessingAncestral sequence reconstruction (ASR) offers a revolutionary approach to resurrect functional proteins, yet its potential in transporter engineering remains underexplored.
Peining Zhang +3 more
doaj +6 more sources
Functional characterization of a xylose transporter in Aspergillus nidulans. [PDF]
Biotechnol Biofuels, 2014 The production of bioethanol from lignocellulosic feedstocks will only become economically feasible when the majority of cellulosic and hemicellulosic biopolymers can be efficiently converted into bioethanol. The main component of cellulose is glucose, whereas hemicelluloses mainly consist of pentose sugars such as D-xylose and L-arabinose. The genomes
Colabardini AC +8 more
europepmc +7 more sources
Comparison of heterologous xylose transporters in recombinant
Biotechnology for Biofuels, 2010 Background Baker's yeast (Saccharomyces cerevisiae) has been engineered for xylose utilization to enable production of fuel ethanol from lignocellulose raw material. One unresolved challenge is that S.
Hahn-Hägerdal Bärbel +2 more
doaj +5 more sources
Engineering of an endogenous hexose transporter into a specific D-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae. [PDF]
Biotechnol Biofuels, 2014 Engineering of Saccharomyces cerevisiae for the simultaneous utilization of hexose and pentose sugars is vital for cost-efficient cellulosic bioethanol production. This yeast lacks specific pentose transporters and depends on endogenous hexose transporters for low affinity pentose uptake.
Nijland JG +5 more
europepmc +7 more sources
An evolved xylose transporter from
Microbial Cell Factories, 2009 Background Xylose is a second most abundant sugar component of lignocellulose besides glucose. Efficient fermentation of xylose is important for the economics of biomass-based biorefineries.
Zhang Jingqing +4 more
doaj +5 more sources
Structural and biochemical insights of xylose MFS and SWEET transporters in microbial cell factories: challenges to lignocellulosic hydrolysates fermentation [PDF]
Frontiers in MicrobiologyThe production of bioethanol from lignocellulosic biomass requires the efficient conversion of glucose and xylose to ethanol, a process that depends on the ability of microorganisms to internalize these sugars.
Iasmin Cartaxo Taveira +8 more
doaj +4 more sources
Engineering of sugar transporters for improvement of xylose utilization during high-temperature alcoholic fermentation in Ogataea polymorpha yeast [PDF]
Microbial Cell Factories, 2020 Background Xylose transport is one of the bottlenecks in the conversion of lignocellulosic biomass to ethanol. Xylose consumption by the wild-type strains of xylose-utilizing yeasts occurs once glucose is depleted resulting in a long fermentation process
Roksolana Vasylyshyn +9 more
doaj +4 more sources
mLife, 2022 Glucose and xylose are two major components of lignocellulose. Simultaneous consumption of glucose and xylose is critical for engineered microorganisms to produce fuels and chemicals from lignocellulosic biomass. Although many production limitations have
Xinna Zhu +7 more
doaj +3 more sources
The role of hexose transporter-like sensor hxs1 and transcription activator involved in carbohydrate sensing azf1 in xylose and glucose fermentation in the thermotolerant yeast Ogataea polymorpha [PDF]
Microbial Cell Factories, 2022 Background Fuel ethanol from lignocellulose could be important source of renewable energy. However, to make the process feasible, more efficient microbial fermentation of pentose sugars, mainly xylose, should be achieved.
Marta V. Semkiv +9 more
doaj +2 more sources