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Y-STR profiling in two Afghanistan populations
Legal Medicine, 2011Afghanistan's unique geostrategic position in Eurasia has historically attracted commerce, conflict and conquest to the region. It was also an important stop along the Silk Road, connecting the far eastern civilizations with the western world. Nevertheless, limited genetic studies have been performed in Afghan populations.
Harlette, Lacau +6 more
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Y-STR Frequency Surveying Method: A critical reappraisal
Forensic Science International: Genetics, 2011Reasonable formalized methods to estimate the frequencies of DNA profiles generated from lineage markers have been proposed in the past years and were discussed in the forensic community. Recently, collections of population data on the frequencies of variations in Y chromosomal STR profiles have reached a new quality with the establishment of the ...
Willuweit, Sascha +3 more
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The highly discriminating Y-STR DYS464: a reasonable extension of the minimal Y-STR haplotype?
International Congress Series, 2004Abstract DYS464 is a multi-copy STR system with four positions on the Y chromosome (DYS464a, b, c, and d) which was recently identified and characterized. The aims of our study were to perform a population study, to estimate the mutation-rate and an extensive sequence analysis in order to confirm the nomenclature.
Burkhard Berger +3 more
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Y-STR typing in forensic analysis
International Congress Series, 2003Abstract We reinvestigated 20 cases of rape/sexual maltreatment from the years 2000/2001 (i.e. 61 different samples) that had already been investigated by STR typing (using Profiler Plus and mentype kit). In 10 cases, male DNA has been detected in stains or vaginal swabs, samples from the other 10 cases did not show any traces of male DNA.
N. von Wurmb-Schwark +2 more
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A comprehensive Y-STR portrait of Yousafzai’s population
International Journal of Legal Medicine, 2017In the current study, 17 Y-Chromosomal short tandem repeats (Y-STRs) included in theAmpFlSTR Y-Filer amplification kit (Applied Biosystems, Foster City, USA) were investigated in 146 unrelated Yousafzai males residing in the Khyber Pakhtunkhwa Province of Pakistan. A total of 94 (89.52%) unique haplotypes were observed.
Sadia, Tabassum +4 more
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Y-STR markers from Ladakh in the Himalayas
Legal Medicine, 2016A total of 223 samples from the general population of Ladakh in Northwestern India were amplified at 17 Y-STR loci using the AmpFlSTR® Yfiler™ system. The DNA profiles generated were employed to generate allelic frequencies, gene diversity, haplotype diversity and discrimination capacity values as well as number of different haplotypes, fraction of ...
David, Perez-Benedico +5 more
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Performance Characteristics of Commercial Y‐STR Multiplex Systems*
Journal of Forensic Sciences, 2007Abstract: In this work, a number of performance checks were carried out to evaluate the efficacy of commercial Y‐short tandem repeats (Y‐STR) kits for casework applications. The study evaluated the sensitivity, specificity and stability of the Y‐STR markers used and the ability to obtain a male profile from postcoital samples taken at various time ...
Mayntz-Press, Kathleen A. +1 more
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AbstractSince Y‐STR typing only amplifies male Y chromosomal DNA, it can simplify the interpretation of some DNA mixtures that contain female DNA. However, if there are multiple male contributors, mixed Y‐STR DNA profiles will often be obtained. Y‐STR mixture analysis cases are particularly challenging though as, currently, there are no validated ...
Kaitlin Huffman +2 more
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Likelihood ratio development for mixed Y-STR profiles
Forensic Science International: Genetics, 2018In this paper we introduce a new likelihood ratio method for evaluating mixed Y-STR profiles that is based on the premise that, given a haplotype has been seen in the person of interest, the most likely source of a second haplotype, matching at all or most loci, is in an individual with a recent common ancestor.
Duncan Taylor +2 more
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Advancement of Y-markers with Rapidly Mutating Y-STR (RM-Y STR)
Abstract: In forensic genetics, the research of Y-chromosomal markers has evolved dramatically, especially with the use of rapidly changing Y STRs (RM-YSTRs). Short tandem repeats on the Y chromosome, or Y-STRs, are frequently employed in forensic casework, population studies, and genealogical research. They have proven to be useful in distinguishingAkansha Dixit +4 more
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