Results 181 to 190 of about 10,690,340 (404)
Background: Cyprus is an island in the Eastern Mediterranean Sea with a documented history of human settlements dating back over 10,000 years. Aim: To investigate the paternal lineages of a representative population from Cyprus in the context of the ...
Cemal Gurkan+6 more
doaj +1 more source
Timing of ancient human Y lineage depends on the mutation rate: A comment on Mendez et al [PDF]
Mendez et al. recently report the identification of a Y chromosome lineage from an African American that is an outgroup to all other known Y haplotypes, and report a time to most recent common ancestor, TMRCA, for human Y lineages that is substantially longer than any previous estimate.
arxiv
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
Microdissection, DOP-PCR amplification and microcloning were used to study the large Y chromosome of Chionodraco hamatus, an Antarctic fish belonging to the Notothenioidei, the dominant component of the Southern Ocean fauna.
Ennio Cocca+4 more
doaj +1 more source
The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation [PDF]
Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertranscribed due to dosage compensation. Here, we dissect the molecular mechanisms and functional pressures driving heterochromatin formation and dosage compensation of the recently formed neo-sex chromosomes ...
arxiv
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Comparison of genetic and linguistic data as an approach to studying human migrations
The origin of humans and their settling around the globe are explored using various scientific methods. Genomic profiling data increasing in volume every day are of particular interest to researchers of these problems.
E.A. Boulygina+2 more
doaj
Centromere reference models for human chromosomes X and Y satellite arrays [PDF]
The human genome remains incomplete, with multi-megabase sized gaps representing the endogenous centromeres and other heterochromatic regions. These regions are commonly enriched with long arrays of near-identical tandem repeats, known as satellite DNAs, that offer a limited number of variant sites to differentiate individual repeat copies across ...
arxiv
Influence of the Y chromosome on gonadal differentiation: asymmetrical gonads in an XO-XY mosaic. [PDF]
Pierre Ferrier, Vincent C. Kelley
openalex +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source