Results 271 to 280 of about 60,617 (307)

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Recent advances on Hippo-YAP pathway in skin diseases. [PDF]

Front Immunol
Cai X, Chen K, Li X, Zhang K, Gu J, Shen C, Yu B, Huang C.   +7 more
europepmc   +1 more source

High prevalence of loss of Claudin‐18 expression in invasive non‐mucinous lung adenocarcinoma: Potential diagnostic implications in routine practice

Histopathology, EarlyView.
Loss of Claudin‐18 (Cldn18) expression is a frequent and specific feature of non‐mucinous lung adenocarcinoma (NM‐LUAD). Cldn18 immunohistochemistry may serve as an ancillary tool for distinguishing malignant from non‐neoplastic alveolar epithelium, as well as for differentiating NM‐LUADs with mucin production from M‐LUADs, particularly in small or ...
Stefano Lucà, Marco Montella, Mario Fordellone, Riccardo Monti, Maria Giulia Disanto, Giuseppa Zannini, Marina Accardo, Maria Ali, Gaetano Di Guida, Carminia Maria Della Corte, Beatrice Leonardi, Severo Campione, Valerio Nardone, Floriana Morgillo, Alfonso Fiorelli, Luisella Righi, Mattia Barbareschi, Luka Brcic, Renato Franco   +18 more
wiley   +1 more source

<i>IGF2BP3</i>-mediated stabilization of <i>RHOA</i> mRNA promotes osteosarcoma proliferation via Hippo signaling. [PDF]

Transl Cancer Res
Wu J, Xia J, Tao Y, Weng Y.
europepmc   +1 more source

Pancreatic cancer: molecular pathogenesis and emerging therapeutic strategies. [PDF]

Signal Transduct Target Ther
Rozengurt E, Eibl G.
europepmc   +1 more source

PKC-eta promotes breast cancer metastasis by regulating the Hippo-YAP signaling pathway. [PDF]

Signal Transduct Target Ther
Liju VB, Waidha K, Muraleedharan A, Jayaram DR, Haimov H, Jagadeeshan S, Manikandan DB, Shareb RA, Nurukurti L, Sklarz M, Gutkind JS, Allon I, Cohen O, Elkabets M, Livneh E.   +14 more
europepmc   +1 more source

Transient proliferation by reversible YAP and mitogen control of the cyclin D1/p27 ratio. [PDF]

Commun Biol
Ferrick KR, Upadhya SW, Fan Y, Ratnayeke N, Teruel MN, Meyer T.   +5 more
europepmc   +1 more source

Oxaliplatin upregulates Cyr61 expression by inhibiting the Hippo-YAP pathway which contributes to drug resistance of colorectal cancer cells. [PDF]

Discov Oncol
Lu P, Zheng C, Zhang J, Zhu X, Chen X, Zhang J, Cao Y, Huang Z.   +7 more
europepmc   +1 more source

FSCN1 induces subchondral bone sclerosis in osteoarthritis via modulating actin cytoskeleton dynamics and YAP signaling. [PDF]

Arthritis Res Ther
Xiao Y, Chen L, Chen D, Li J, Cheng Q, Yang P, Zou Z, Wu J, Li K, Yang C, Wang H, Yang C.   +11 more
europepmc   +1 more source