Results 281 to 290 of about 60,617 (307)

Abstract 919: Intercalated Disk Protein Xin-beta is Required for the Hippo/YAP Signaling in the Heart

open access: closedCirculation Research, 2019
Cardiovascular diseases continue to be a leading cause of death and disability. Despite this alarming fact, there is lack of effectual treatment and the molecular mechanisms underlying these devastating diseases remain elusive. Intercalated disk (ICD) is not only essential for the integrity of cardiomyocytes to withstand the strong mechanical forces ...
Haipeng Guo   +13 more
openaire   +2 more sources
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TNFAIP3 Interacting Protein 3 Is an Activator of Hippo‐YAP Signaling Protecting Against Hepatic Ischemia/Reperfusion Injury

Hepatology, 2021
Background and Aims Hepatic ischemia/reperfusion (I/R) injury, a common clinical problem that occurs during liver surgical procedures, causes a large proportion of early graft failure and organ rejection cases. The identification of key regulators of hepatic I/R injury may provide potential strategies to clinically improve the ...
Junjie Zhou   +22 more
openaire   +2 more sources

Abstract 17308: Effect of HIV Protein-Tat & Cocaine on Hippo-YAP Signaling Axis in Pulmonary Arterial Smooth Muscle Cells

Circulation, 2018
Introduction and hypothesis: Intravenous drug use (IVDU) is considered to be one of the important risk factors in the development of HIV-associated pulmonary arterial hypertension (HPAH). Our previous findings demonstrate that the exposure of cocaine to HIV infected individuals has an additive effect in enhancing the ...
Aradhana Mohan   +3 more
openaire   +1 more source

Zinc finger protein 367 exerts a cancer-promoting role in small cell lung cancer by influencing the CIT/LATS2/YAP signaling cascade

Toxicology and Applied Pharmacology
A remarkable cancer-related role of zinc finger protein 367 (ZNF367) has been demonstrated in multiple malignancies. However, whether ZNF367 has a role in small-cell lung cancer (SCLC) remains unexplored. The purpose of this work was to explore the potential role and mechanism of ZNF367 in SCLC. In silico analysis using the Gene Expression Omnibus (GEO)
Ranran, Kong   +11 more
openaire   +2 more sources

Control of stem cell renewal and fate by YAP and TAZ

Nature Reviews Molecular Cell Biology, 2023
Jordan Driskill, Duojia Pan
exaly  

An overview of signaling pathways regulating YAP/TAZ activity

Cellular and Molecular Life Sciences, 2020
Boon Chin Heng, Xuehui Zhang, Yan Wei
exaly  

Deficiency of vitamin D-binding protein exacerbates liver fibrosis by disrupting iron homeostasis via the activation of YAP signaling

Experimental Cell Research
Qing Zheng   +8 more
openaire   +1 more source

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