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The Hippo Signaling Pathway, Reactive Oxygen Species Production, and Oxidative Stress: A Two-Way Traffic Regulation [PDF]

Cells
The Hippo signaling pathway is recognized for its significant role in cell differentiation, proliferation, survival, and tissue regeneration. Recently, the Hippo signaling pathway was also found to be associated with oxidative stress and reactive oxygen ...
Bella Amanda, Rangga Pragasta, Haris Cakrasana, Arifa Mustika, Zakiyatul Faizah, Delvac Oceandy   +5 more
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Hippo signaling pathway and respiratory diseases

Cell Death Discovery, 2022
The hippo signaling pathway is a highly conserved evolutionary signaling pathway that plays an important role in regulating cell proliferation, organ size, tissue development, and regeneration.
Weifeng Tang, Min Li, Xiaoting Yangzhong, Xifeng Zhang, Anju Zu, Yunjiao Hou, Lin Li, Shibo Sun   +7 more
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The critical role of the Hippo signaling pathway in kidney diseases

Frontiers in Pharmacology, 2022
The Hippo signaling pathway is involved in cell growth, proliferation, and apoptosis, and it plays a key role in regulating organ size, tissue regeneration, and tumor development.
Yuting Sun, De Jin, Ziwei Zhang, Di Jin, JiaoJiao Xue, LiYun Duan, YuQing Zhang, XiaoMin Kang, FengMei Lian, FengMei Lian   +9 more
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Hippo Signaling Pathway in Gliomas

Cells, 2021
The Hippo signaling pathway is a highly conserved pathway involved in tissue development and regeneration that controls organ size through the regulation of cell proliferation and apoptosis.
Lucie Karayan Tapon, Pierre-Olivier Guichet, Konstantin Masliantsev   +2 more
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The Hippo Signaling Pathway in Drug Resistance in Cancer

Cancers, 2021
Simple Summary Although great breakthroughs have been made in cancer treatment following the development of targeted therapy and immune therapy, resistance against anti-cancer drugs remains one of the most challenging conundrums.
Jixin Dong, Dong Jixin
exaly   +2 more sources

The Hippo signaling pathway in development and regeneration

Cell Reports
Summary: The Hippo signaling pathway is a central growth control mechanism in multicellular organisms. By integrating diverse mechanical, biochemical, and stress cues, the Hippo pathway orchestrates proliferation, survival, differentiation, and mechanics
Zhenxing Zhong, Zhihan Jiao, Fa-Xing Yu
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The Hippo Signaling Pathway in Development and Disease

Developmental Cell, 2019
The Hippo signaling pathway regulates diverse physiological processes, and its dysfunction has been implicated in an increasing number of human diseases, including cancer.
Yonggang Zheng, Duojia Pan
exaly   +2 more sources

The Hippo signaling pathway as a therapeutic target in Alzheimer’s disease [PDF]

Molecular Neurodegeneration
The Hippo signaling pathway is well-known for its regulation of organ size, cell proliferation, apoptosis, and cell migration and differentiation. Recent studies have demonstrated that Hippo signaling also plays important roles in the nervous system ...
Doris Chen, Stella Wigglesworth-Littlewood, Frank J. Gunn-Moore   +2 more
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KSR1 is a scaffold for the Hippo signaling pathway [PDF]

Communications Biology
The evolutionarily conserved Hippo signaling pathway regulates organ size and tissue homeostasis. Yes-associated protein (YAP) functions as a transcriptional co-activator and is a critical downstream effector of the Hippo signaling pathway.
Samar Sayedyahossein, Mohammed Rizwan Babu Sait, Zhigang Li, Riddhi Banerjee, Andy Tran, Louise Thines, Mehdi Karimi, Mehrnoosh Bahmani, Naomi Mishan, Pooya Borzou, Sergio A. Hassan, David B. Sacks   +11 more
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The Hippo signaling pathway modulates pancreatic tissue homeostasis [PDF]

Cell Death Discovery
The Hippo signaling pathway, a highly conserved signaling cascade from Drosophila to mammals, plays a critical role in mammals in regulating cell proliferation, senescence and apoptosis.
Xiaoyan Wang, Jiajing Du, Haiyun Li, Zhiwei Cao, Zhonghua Cheng, Zuoyun Wang   +5 more
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