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Tumor Cell-Derived CXCL2 Potentiates Neutrophil-Mediated Antitumor Immunity by Inhibiting Cholesterol Biosynthesis in Hepatocellular Carcinoma. [PDF]

open access: yesAdv Sci (Weinh)
Liu X   +13 more
europepmc   +1 more source

α-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers. [PDF]

open access: yesNat Chem Biol
Mi W   +21 more
europepmc   +1 more source
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Proteomic analysis of zebrafish folliculogenesis identifies YB-1 (Ybx1/ybx1) as a potential gatekeeping molecule controlling early ovarian folliculogenesis

Biology of Reproduction, 2023
Abstract As in mammals, ovarian folliculogenesis in teleosts also consists of two phases: the primary growth (PG) and secondary growth (SG) phases, which are analogous to the preantral and antral phases respectively in mammals. In this study, we performed a proteomic analysis on zebrafish follicles undergoing the PG–SG transition aiming ...
Esther Shuk-Wa, Lau   +4 more
openaire   +2 more sources

Pathogenetic Significance of YBX1 Expression in Acute Myeloid Leukemia Relapse

Current Research in Translational Medicine, 2022
Genomic abnormalities were established as prognostic and diagnostic markers for acute myeloid leukemia (AML) tumorgenesis and YBX1 gene has important roles in different cancer types.A total of 109 adult and pediatric patients with De novo AML, were enrolled in this study.
Mahmoud B Y, Gouda   +3 more
openaire   +2 more sources

YBX1 Promotes MSC Osteogenic Differentiation by Activating the PI3K/AKT Pathway

Current Stem Cell Research & Therapy, 2023
Introduction: Bone metabolism has an essential role in the bone disease, but its specific mechanism remains unclear. Y-Box Binding Protein 1 (YBX1) is a gene with broad nucleic acid binding properties, which encodes a highly conserved cold shock domain protein. Previous studies have shown that YBX1 is closely related to cell differentiation.
Jiayu, Chen   +7 more
openaire   +2 more sources

YBX1 knockdown induces renal cell carcinoma cell apoptosis via Kindlin-2

Cell Cycle, 2021
Among urological tumors, renal cell carcinoma (RCC) is the third-highest mortality rate tumor, and 20%-30% of RCC patients present with metastases at the time of diagnosis. While the treatment of RCC has been improved over the last few years, its mortality stays high.
Qiqi, Cui   +10 more
openaire   +2 more sources

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