Results 181 to 190 of about 6,571 (196)
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Myocardial YBX1 is dispensable for cardiac development and function
American Journal of Physiology-Heart and Circulatory PhysiologyThis study presents a genetic, cardiomyocyte-specific Ybx1 loss-of-function mouse model, addressing limitations of prior RNA interference (RNAi) approaches. Global YBX1 deletion causes embryonic lethality with severe cardiac malformations, whereas cardiomyocyte-specific deletion results in only transient embryonic noncompaction that resolves with ...
Elise V. Stanley +5 more
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RNA m5C methylation mediated by Ybx1 ensures hematopoietic stem and progenitor cell expansion
Cell ReportsOur research hypothesis posits that RNA m5C methylation, mediated by Ybx1, plays a critical role in ensuring the expansion of hematopoietic stem and progenitor cells (HSPCs).
Lu Wang, Suwei Gao, Mengyao Liu
exaly +2 more sources
USP47 stabilizes YBX1 to promote the progression of acute myeloid leukemia
Oncogene, 2023Hu Lei +5 more
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YBX1 Underwent Phase Separation into Stress Granules Stimulated by Ionizing Radiation
Radiation ResearchStress granules (SGs) are formed through liquid-liquid phase separation (LLPS), in response to external stimuli. YBX1, an integral component of SGs, plays a crucial role in tumor progression and cellular stress response. This study aims to elucidate the mechanisms and specific biological implications of YBX1 in SG formation, along with the ...
Jiaxin, Tang +4 more
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Transcriptional activation of NANOG by YBX1 promotes lung cancer stem-like properties and metastasis
Biochemical and Biophysical Research Communications, 2017Jinxiu Li, Chundong Gu, Jing Kong
exaly