Results 21 to 30 of about 697,024 (293)

Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

open access: yeseLife, 2020
Cytokinesis, which enables the physical separation of daughter cells once mitosis has been completed, is executed in fungal and animal cells by a contractile actin- and myosin-based ring (CAR).
Elisa Gómez-Gil   +9 more
doaj   +1 more source

Risk Factors for Fungal Co-Infections in Critically Ill COVID-19 Patients, with a Focus on Immunosuppressants

open access: yesJournal of Fungi, 2021
Severe cases of coronavirus disease 2019 (COVID-19) managed in the intensive care unit are prone to complications, including secondary infections with opportunistic fungal pathogens.
Obinna T. Ezeokoli   +2 more
doaj   +1 more source

Physiological characteristics of a high amylase-producing Saccharomycopsis fibuligera [PDF]

open access: yesZhongguo niangzao
In order to develop a strain suitable for brewing environments, reducing production input costs, and enhancing the flavor of fermentation products, a high amylase-producing strain AMCC32244 was isolated and screened from old rice wine.
SUN Yafang, ZHANG Jingjie, GUO Tianfen, ZHANG Yan, QIN Xianwu
doaj   +1 more source

Decreased Vacuolar Ca2+ Storage and Disrupted Vesicle Trafficking Underlie Alpha-Synuclein-Induced Ca2+ Dysregulation in S. cerevisiae

open access: yesFrontiers in Genetics, 2020
The yeast Saccharomyces cerevisiae is a powerful model to study the molecular mechanisms underlying α-synuclein (α-syn) cytotoxicity. This is due to the high degree of conservation of cellular processes with higher eukaryotes and the fact that yeast does
Geert Callewaert   +7 more
doaj   +1 more source

Introducing a Simple Method to Investigate Relative Volatilities of Flavour Compounds in Fruit Brandies

open access: yesBeverages, 2023
Determination of relative volatilities of flavour compounds in hydro-alcoholic solutions is usually performed by time-consuming and costly standard methods such as the Gillespie dynamic recirculation method. This study tested a quick and easy method with
Manami Yagishita   +2 more
doaj   +1 more source

Multiple Antibiotic Resistance Plasmids Allow Scalable, PCR-Mediated DNA Manipulation and Near-Zero Background Cloning

open access: yesFood Technology and Biotechnology, 2016
We have constructed two plasmids that can be used for cloning as templates for PCR-based gene disruption, mutagenesis and the construction of DNA chromosome translocation cassettes.
Remigiusz Arnak   +3 more
doaj   +1 more source

The Significance of Lipids to Biofilm Formation in Candida albicans: An Emerging Perspective

open access: yesJournal of Fungi, 2018
Candida albicans, the dimorphic opportunistic human fungal pathogen, is capable of forming highly drug-resistant biofilms in the human host. Formation of biofilm is a multistep and multiregulatory process involving various adaptive mechanisms.
Darakshan Alim   +2 more
doaj   +1 more source

Identification of novel microtubule inhibitors effective in fission yeast and human cells and their effects on breast cancer cell lines

open access: yesOpen Biology, 2021
Microtubules are critical for a variety of cellular processes such as chromosome segregation, intracellular transport and cell shape. Drugs against microtubules have been widely used in cancer chemotherapies, though the acquisition of drug resistance has
Jun Morishita, Paul Nurse
doaj   +1 more source

Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells

open access: yesOpen Biology, 2023
The Rho GTPase family proteins are key regulators of cytoskeletal dynamics. Deregulated activity of Rho GTPases is associated with cancers and neurodegenerative diseases, and their potential as drug targets has long been recognized. Using an economically
Jun Morishita, Paul Nurse
doaj   +1 more source

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