Results 291 to 300 of about 1,379,653 (337)

Metabolic Engineering of the 5‐Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein‐Based Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
We have engineered the heme biosynthetic pathway in E. coli to develop an efficient cofactor supplementation system for hemoproteins. Through the incorporation of the heterogeneous C4 pathway, the engineered cells significantly increase the expression levels of active holohemoproteins and enhance the efficiency of whole‐cell and lysate‐based ...
Shunsuke Kato   +6 more
wiley   +1 more source

Integrated Chemoenzymatic Synthesis of the mRNA Vaccine Building Block N1‐Methylpseudouridine Triphosphate

open access: yesAngewandte Chemie International Edition, EarlyView.
Pseudouridine‐5′‐triphosphate (ΨTP) and its N1‐methylated derivative (m1ΨTP) are crucial components in mRNA vaccine technology. Here, an atom‐economic, high‐yielding biocatalytic route for ΨTP synthesis is presented. A new chemoenzymatic route for m1ΨTP synthesis was developed.
Martin Pfeiffer   +4 more
wiley   +1 more source

Proteomic and <i>N</i>-glycomic comparison of synthetic and bovine whey proteins and their effect on human gut microbiomes <i>in vitro</i>. [PDF]

open access: yesMicrobiol Spectr
Bolino M   +8 more
europepmc   +1 more source

Striking mycotoxin tolerance and zearalenone elimination capacity of the decaying wood associated yeast Sugiyamaella novakii (Trichomonascaceae). [PDF]

open access: yesBMC Microbiol
Acs-Szabo L   +12 more
europepmc   +1 more source

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast. [PDF]

open access: yesProtein Sci
Benning FMC   +11 more
europepmc   +1 more source

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