Results 41 to 50 of about 1,336,378 (359)
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells
Open Biology, 2023 The Rho GTPase family proteins are key regulators of cytoskeletal dynamics. Deregulated activity of Rho GTPases is associated with cancers and neurodegenerative diseases, and their potential as drug targets has long been recognized. Using an economically
Jun Morishita, Paul Nurse
doaj +1 more source
Lattice-based simulation of the effects of nutrient concentration and magnetic field exposure on yeast colony growth and morphology [PDF]
arXiv, 2021 Yeasts exist in communities that expand over space and time to form complex structures and patterns. We developed a computational lattice-based framework to perform spatial-temporal simulations of budding yeast colonies exposed to different nutrient and magnetic field conditions. The budding patterns of haploid and diploid yeast cells were incorporated
arxiv
A new framework for identifying combinatorial regulation of transcription factors: a case study of the yeast cell cycle [PDF]
Journal of Biomedical Informatics Volume 40, Issue 6, December
2007, Pages 707-725. Intelligent Data Analysis in Biomedicine, 2010 By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activities using a singular value decomposition method and reducing high-dimensional input gene space by considering genomic properties of gene clusters.
arxiv +1 more source
Molecules and Cells, 2001 The large number of signaling pathways and regulatory proteins that affect transcription highlights a need for funneling of information since transcription of all protein encoding genes is executed by the same set of general transcription factors and RNA polymerase II.
Björklund, Stefan +2 more
openaire +3 more sources
BMC Microbiology, 2021 Background Translation is an important point of regulation in protein synthesis. However, there is a limited number of methods available to measure global translation activity in yeast. Recently, O-propargyl-puromycin (OPP) labelling has been established
Jennifer Staudacher +2 more
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Nonspecific Protein-DNA Binding Is Widespread in the Yeast Genome [PDF]
Biophysical Journal 102(8), 1881-1888 (2012), 2012 Recent genome-wide measurements of binding preferences of ~200 transcription regulators in the vicinity of transcription start sites in yeast, have provided a unique insight into the cis- regulatory code of a eukaryotic genome (Venters et al., Mol. Cell 41, 480 (2011)).
arxiv +1 more source
Fermentation, 2017 Yeasts are truly fascinating microorganisms. Due to their diverse and dynamic activities, they have been used for the production of many interesting products, such as beer, wine, bread, biofuels, and biopharmaceuticals. Saccharomyces cerevisiae (brewers’ or bakers’ yeast) is the yeast species that is surely the most exploited by man.[...]
openaire +4 more sources
Impact of particle size reduction on high gravity enzymatic hydrolysis of steam-exploded wheat straw
SN Applied Sciences, 2021 Article Highlights Fiber size reduction benefits enzymatic high gravity hydrolysis of steam-exploded wheat straw. Small fiber size of ≤ 2.5 mm enables saccharification at 35% w/w solid loadings.
Luis Hoppert, Daniel Einfalt
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A dynamic fluid landscape mediates the spread of bacteria [PDF]
arXiv, 2023 Microbial interactions regulate their spread and survival in competitive environments. It is not clear if the physical parameters of the environment regulate the outcome of these interactions. In this work, we show that the opportunistic pathogen Pseudomonas aeruginosa occupies a larger area on the substratum in the presence of yeast such as ...
arxiv