Results 91 to 100 of about 845,439 (243)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

The control of mitochondrial morphology and dynamics in Arabidopis thaliana [PDF]

, 2012
Mitochondria are ubiquitous eukaryotic organelles which carry out a range of essential functions, most notably the production of ATP through the process of oxidative phosphorylation.
Scott, Iain
core   +2 more sources

A yeast synthetic network for In-vivo Reverse-engineering and Modelling Assessment (IRMA) [PDF]

, 2009
Systems Biology approaches aim to reconstruct gene regulatory networks from experimental data. Conversely, Synthetic Biology aims at using mathematical models to design novel biological ‘circuits’ (synthetic networks) in order to seed new functions ...
Cantone, Irene
core   +1 more source

Secure biosystems design in Saccharomyces cerevisiae establishes effective biocontainment strategies and mechanisms of escape

Applied and Environmental Microbiology
The widespread application of recombinant DNA and synthetic biology approaches for microbial metabolic engineering pursuits has motivated the development of biocontainment strategies, targeting safe and secure deployment of genetically modified ...
Natalie A. Lamb, Kimberly A. Rosenbach, Thomas J. Musselwhite, Kathleen L. Arnolds, Riley C. Higgins, Gabriella A. Li, Jeffrey G. Linger, Michael T. Guarnieri   +7 more
doaj   +1 more source

Yeast and its uses.

Kvasný průmysl, 2012
Yeasts are eukaryotic heterotrophic organisms belonging to fungi. In contrast to other eukaryotes yeasts possess thick and rigid cell wall. As a source of carbon and energy yeast can degrade sugars using two metabolic pathways: aerobic respiration and ...
Jana KOPECKÁ, Dagmar MATOULKOVÁ, Miroslav NĚMEC   +2 more
doaj   +1 more source

Renewing Lost Genetic Variability with a Classical Yeast Genetics Approach. [PDF]

J Fungi (Basel), 2023
Gupte AP, Pierantoni DC, Conti A, Donati L, Basaglia M, Casella S, Favaro L, Corte L, Cardinali G.   +8 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia

Frontiers in Oncology, 2017
In mammalian organisms liquid tumors such as acute myeloid leukemia (AML) are related to spontaneous chromosomal translocations ensuing in gene fusions.
Valentina Tosato, Valentina Tosato, Valentina Tosato, Nicole West, Jan Zrimec, Dmitri V. Nikitin, Giannino Del Sal, Roberto Marano, Michael Breitenbach, Carlo V. Bruschi, Carlo V. Bruschi   +10 more
doaj   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source