Results 71 to 80 of about 845,439 (243)

Central carbon metabolism of the biocontrol yeast Pichia anomala [PDF]

, 2004
The biocontrol yeast Pichia anomala prevents mould damage of moist cereal grain during malfunctioning airtight storage but it can also spoil food and feed. This thesis focuses on the physiology and metabolism of P.
Fredlund, Elisabeth
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
Adam-Vizi, Vera, Monika Wysocka-Kapcinska (368157), Christos Chinopoulos (317665), Roza Kucharczyk (141980), Christos Chinopoulos, Cynthia L David, Chinopoulos Christos, Hunt AM, Vekey, Karoly, Beata Torocsik (317661), Hunt Andrea M., Roza Kucharczyk, Karoly Vekey (5656285), Kucharczyk Roza, Wysocka-Kapcinska M, Cynthia L. David, Vera Adam-Vizi (317663), Vékey Károly, Cynthia L. David (461150), Törőcsik Beáta, Ádám Veronika, Monika Wysocka-Kapcinska, Andrea M. Hunt, Wysocka-Kapcinska, Monika, Lilla Turiak, Tsaprailis, George, David Cynthia L., Törőcsik, Beáta, Turiák, Lilla, Tsaprailis George, Andrea M. Hunt (461151), Wysocka-Kapcinska Monika, Beata Torocsik, Vera Adam-Vizi, George Tsaprailis (268492), Ádám, Veronika, Kucharczyk R, Andrea M Hunt, David CL, George Tsaprailis, Tsaprailis G, Chinopoulos, Christos, Turiák Lilla, Hunt, Andrea M., Lilla Turiak (5656282), Kucharczyk, Roza, David, Cynthia L., Karoly Vekey, Adam-Vizi Vera   +48 more
core   +2 more sources

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Cells expressing murine RAD52 splice variants favor sister chromatid repair [PDF]

, 2006
The RAD52 gene is essential for homologous recombination in the yeast Saccharomyces cerevisiae. RAD52 is the archetype in an epistasis group of genes essential for DNA damage repair.
Freeman, TC, Savitzky, MH, Sunjevaric, [No Value], Rothstein, R, Marrero, VA, Thorpe, PH   +5 more
core   +1 more source

Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System [PDF]

, 2009
In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths
Zimnicka, Magdalena, Joanna Kaminska, Burzynska, Beata, Kania Magdalena, Wysocka-Kapcinska, Monika, Beata Burzynska, Witold Danikiewicz, Danikiewicz Witold, Plochocka, Danuta, Leszczynska, Agata, Leszczynska Agata, Zimnicka Magdalena, Danikiewicz, Witold, Wysocka-Kapcinska Monika, Magdalena Kania, Kiliszek Marek, Marek Kiliszek, Kaminska Joanna, Agata Leszczynska, Danuta Plochocka, Magdalena Zimnicka, Kaminska, Joanna, Plochocka Danuta, Szkopinska, Anna, Anna Szkopinska, Kania, Magdalena, Kiliszek, Marek, Szkopinska Anna, Monika Wysocka-Kapcinska, Burzynska Beata   +29 more
core   +3 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Impact of Yeast Glycosylation Pathway on Cell Integrity and Morphology, Glycosylation, Stefana Petrescu (Ed.), ISBN: 978-953-51-0771-2, InTech, Available from: http://www.intechopen.com/books/glycosylation/impact-of-yeast-glycosylation-pathway-on-cell-integrity-and-morphology [PDF]

, 2012
Protein glycosylation is a multi step reaction, well conserved in the eukaryotic cells. In N-glycosylation reactions dolichyl phosphate (DolP) serves as a lipid acceptor of sugar residues forming DolPPGlcNAc2Man9Glc3.
Palamarczyk, Grazyna, Juchimiuk, Mateusz, Pasikowska, Monika, Janik, Anna, Orłowski, Jacek, Kruszewska, Joanna S.   +5 more
core   +1 more source

Dual control of NAD+ synthesis by purine metabolites in yeast

eLife, 2019
Metabolism is a highly integrated process resulting in energy and biomass production. While individual metabolic routes are well characterized, the mechanisms ensuring crosstalk between pathways are poorly described, although they are crucial for ...
Benoît Pinson, Johanna Ceschin, Christelle Saint-Marc, Bertrand Daignan-Fornier   +3 more
doaj   +1 more source