Results 91 to 100 of about 67,575 (268)
AsymptomaticYersinia pestisInfection, China [PDF]
To the Editor: Plague is one of the oldest identifiable diseases. Modern public health measures and effective antimicrobial treatments have led to a decrease in plague cases worldwide. However, plague remains endemic in many natural foci. Since the early 1990s, the World Health Organization (WHO) has reported a steadily increasing trend in human plague
Bei Li+6 more
openaire +3 more sources
Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector [PDF]
BACKGROUND: Toxin complex (Tc) family proteins were first identified as insecticidal toxins in Photorhabdus luminescens and have since been found in a wide range of bacteria.
B Joseph Hinnebusch+5 more
core +1 more source
Ail provides multiple mechanisms of serum resistance to Yersinia pestis
Ail, a multifunctional outer membrane protein of Yersinia pestis, confers cell binding, Yop delivery and serum resistance activities. Resistance to complement proteins in serum is critical for the survival of Y.
Joshua J. Thomson+2 more
semanticscholar +1 more source
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling.
Dmitry Ratner+12 more
semanticscholar +1 more source
Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.
When draining lymph nodes become infected by Yersinia pestis (Y. pestis), a massive influx of phagocytic cells occurs, resulting in distended and necrotic structures known as buboes. The bubonic stage of the Y.
Mohammad Arifuzzaman+5 more
semanticscholar +1 more source
The genome of the medieval Black Death agent (extended abstract)
The genome of a 650 year old Yersinia pestis bacteria, responsible for the medieval Black Death, was recently sequenced and assembled into 2,105 contigs from the main chromosome.
Chauve, Cedric+2 more
core +1 more source
Yersiniae Virulence Factors: Type III Secretion System [PDF]
Several Gram-negative pathogenic bacteria have evolved a complex protein secretion system termed the Type Three Secretion System (TTSS) to deliver bacterial effector proteins into host-cells that then modulate host-cellular functions.
Blanco, Jessica
core +1 more source
Avoiding Pandemic Fears in the Subway and Conquering the Platypus. [PDF]
Metagenomics is increasingly used not just to show patterns of microbial diversity but also as a culture-independent method to detect individual organisms of intense clinical, epidemiological, conservation, forensic, or regulatory interest.
Gonzalez, A+5 more
core +2 more sources
Yersinia pestis Survival and Replication in Potential Ameba Reservoir
Plague ecology is characterized by sporadic epizootics, then periods of dormancy. Building evidence suggests environmentally ubiquitous amebae act as feral macrophages and hosts to many intracellular pathogens.
D. W. Markman+6 more
semanticscholar +1 more source
The enteropathogen Yersinia pseudotuberculosis and the related plague agent Y. pestis require the Ysc type III secretion system (T3SS) to subvert phagocyte defense mechanisms and cause disease.
Diana Hooker-Romero+9 more
doaj +1 more source