Results 91 to 100 of about 3,619 (189)

Experimental characterization and prediction of Escherichia coli host cell proteome retention during preparative chromatography

Biotechnology and Bioengineering, Volume 121, Issue 12, Page 3848-3859, December 2024.
Abstract Purification of recombinantly produced biopharmaceuticals involves removal of host cell material, such as host cell proteins (HCPs). For lysates of the common expression host Escherichia coli (E. coli) over 1500 unique proteins can be identified.
Roxana Disela, Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke Klijn, Martin Pabst, Marcel Ottens   +6 more
wiley   +1 more source

Factors influencing cognitive function in Chinese elderly individuals: The role of traditional Chinese medicine in a large-scale cross-sectional study

Journal of Traditional Chinese Medical Sciences
Objective: To identify key factors influencing cognitive function in the elderly, including traditional Chinese medicine (TCM) constitutional classification, and to rank their relative importance.
Houqin Li, Ran Chen, Jing Xia, Feiyu He, Yan Zhang, Shulan Tang, Cheng Ni   +6 more
doaj   +1 more source

Phytobacter diazotrophicus from Intestine of Caenorhabditis elegans Confers Colonization-Resistance against Bacillus nematocida Using Flagellin (FliC) as an Inhibition Factor

Pathogens, 2022
Symbiotic microorganisms in the intestinal tract can influence the general fitness of their hosts and contribute to protecting them against invading pathogens.
Qiuhong Niu, Suyao Liu, Mingshen Yin, Shengwei Lei, Fabio Rezzonico, Lin Zhang   +5 more
doaj   +1 more source

Localization of proteins involved in the biogenesis and repair of the photosynthetic apparatus to thylakoid subdomains in Arabidopsis

Plant Direct, Volume 8, Issue 11, November 2024.
Abstract Thylakoid membranes in chloroplasts and cyanobacteria harbor the multisubunit protein complexes that catalyze the light reactions of photosynthesis. In plant chloroplasts, the thylakoid membrane system comprises a highly organized network with several subcompartments that differ in composition and morphology: grana stacks, unstacked stromal ...
Prakitchai Chotewutmontri, Alice Barkan
wiley   +1 more source

Escherichia coli YidC is a membrane insertase for Sec‐independent proteins [PDF]

The EMBO Journal, 2004
YidC is a recently discovered bacterial membrane protein that is related to the mitochondrial Oxa1p and the Alb3 protein of chloroplasts. These proteins are required in the membrane integration process of newly synthesized proteins that do not require the classical Sec machinery.
Justyna, Serek, Gabriele, Bauer-Manz, Gabriele, Struhalla, Lambertus, van den Berg, Dorothee, Kiefer, Ross, Dalbey, Andreas, Kuhn   +6 more
openaire   +2 more sources

The contribution of mRNA targeting to spatial protein localization in bacteria

The FEBS Journal, Volume 291, Issue 21, Page 4639-4659, November 2024.
mRNA‐based targeting serves as a back‐up strategy for the canonical signal sequence‐based protein targeting in bacteria. While signal sequence‐based targeting depends on dedicated protein‐targeting factors, mRNAs encoding inner membrane proteins can bind directly to protein translocases.
Wenkang Shang, Elisabeth Lichtenberg, Andreea Mihaela Mlesnita, Annegret Wilde, Hans‐Georg Koch   +4 more
wiley   +1 more source

YidC is required for the assembly of the MscL homopentameric pore [PDF]

The FEBS Journal, 2009
The mechanosensitive channel with large conductance (MscL) of Escherichia coli is formed by a homopentameric assembly of MscL proteins. Here, we describe MscL biogenesis as determined using in vivo approaches. Evidence is presented that MscL is targeted to the inner membrane via the signal recognition particle (SRP) pathway, and is inserted into the ...
Pop, Ovidiu I., Soprova, Zora, Koningstein, Gregory, Scheffers, Dirk-Jan, Ulsen, Peter van, Wickström, David, Gier, Jan-Willem de, Luirink, Joen   +7 more
openaire   +3 more sources

Traditional Chinese medicine constitution and cardiometabolic multimorbidity: a nationwide cross-sectional study in older adults

Frontiers in Public Health
ObjectiveCardiometabolic multimorbidity (CMM), defined as the coexistence of two or more cardiometabolic diseases, is increasingly prevalent in older adults.
Ran Chen, Hou-Qin Li, Jing Xia, Jing Xia, Fei-Yu He, Yan Zhang, Zheng Wang, Hong-Yi Zhang, Yao-Ming Yang, Ming-Hua Bai, Cheng Ni   +10 more
doaj   +1 more source

Geranylgeranylated‐chlorophyll‐protein complexes in lhl3 mutant of the green alga Chlamydomonas reinhardtii

The Plant Journal, Volume 120, Issue 4, Page 1577-1590, November 2024.
Significance Statement One of the latest steps of chlorophyll synthesis is the hydrogenation of geranylgeranyl chlorophylls (ChlsGG) to phytylated chlorophylls (Chls) by geranylgeranyl reductase (GGR). We have isolated a pale green mutant, which is unable to grow photoautotrophically and accumulates ChlsGG, from the green alga Chlamydomonas reinhardtii.
Sireesha Kodru, Sreedhar Nellaepalli, Shin‐Ichiro Ozawa, Chihiro Satoh, Hiroshi Kuroda, Ryouichi Tanaka, Katharine Guan, Marilyn Kobayashi, Phoi Tran, Sarah McCarthy, Setsuko Wakao, Krishna K. Niyogi, Yuichiro Takahashi   +12 more
wiley   +1 more source

Defining the Regions of Escherichia coli YidC That Contribute to Activity [PDF]

Journal of Biological Chemistry, 2003
The YidC/Oxa1/Alb3 family of proteins catalyzes membrane protein insertion in bacteria, mitochondria, and chloroplasts. In this study, we investigated which regions of the bacterial YidC protein are important for its function in membrane protein biogenesis.
Fenglei, Jiang, Minyong, Chen, Liang, Yi, Jan-Willem, de Gier, Andreas, Kuhn, Ross E, Dalbey   +5 more
openaire   +2 more sources