Results 101 to 110 of about 3,619 (189)

Protein insertion into the inner membrane of mitochondria: routes and mechanisms

FEBS Open Bio, Volume 14, Issue 10, Page 1627-1639, October 2024.
Proteins of the inner membrane of mitochondria can embark on three distinct import pathways that direct them into the inner membrane. This review describes the machinery and mechanisms by which proteins are inserted into the inner membrane by the TIM22 complex from the intermembrane space, by lateral insertion from the TIM23 complex or by conservative ...
Büsra Kizmaz, Annika Nutz, Annika Egeler, Johannes M. Herrmann   +3 more
wiley   +1 more source

Metabolic activities of marine ammonia‐oxidizing archaea orchestrated by quorum sensing

mLife, Volume 3, Issue 3, Page 417-429, September 2024.
Abstract Ammonia‐oxidizing archaea (AOA) play crucial roles in marine carbon and nitrogen cycles by fixing inorganic carbon and performing the initial step of nitrification. Evaluation of carbon and nitrogen metabolism popularly relies on functional genes such as amoA and accA.
Olivier Pereira, Wei Qin, Pierre E. Galand, Didier Debroas, Raphael Lami, Corentin Hochart, Yangkai Zhou, Jin Zhou, Chuanlun Zhang   +8 more
wiley   +1 more source

Schizosaccharomyces pombe as a fundamental model for research on mitochondrial gene expression: Progress, achievements and outlooks

IUBMB Life, Volume 76, Issue 7, Page 397-419, July 2024.
Abstract Schizosaccharomyces pombe (fission yeast) is an attractive model for mitochondrial research. The organism resembles human cells in terms of mitochondrial inheritance, mitochondrial transport, sugar metabolism, mitogenome structure and dependence of viability on the mitogenome (the petite‐negative phenotype).
Nhu Dinh, Nathalie Bonnefoy
wiley   +1 more source

Identification of YidC Residues That Define Interactions with the Sec Apparatus [PDF]

Journal of Bacteriology, 2013
In bacteria, a subset of membrane proteins insert into the membrane via the Sec apparatus with the assistance of the widely conserved essential membrane protein insertase YidC. After threading into the SecYEG translocon, transmembrane segments of nascent proteins are thought to exit the translocon via a lateral gate in SecY, where YidC facilitates ...
Zaoping, Li, Dana, Boyd, Martin, Reindl, Marcia B, Goldberg   +3 more
openaire   +2 more sources

Shaping the lipid composition of bacterial membranes for membrane protein production

Microbial Cell Factories, 2019
Background The overexpression and purification of membrane proteins is a bottleneck in biotechnology and structural biology. E. coli remains the host of choice for membrane protein production.
Kerstin Kanonenberg, Jorge Royes, Alexej Kedrov, Gereon Poschmann, Federica Angius, Audrey Solgadi, Olivia Spitz, Diana Kleinschrodt, Kai Stühler, Bruno Miroux, Lutz Schmitt   +10 more
doaj   +1 more source

Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor [PDF]

, 2010
We report the 'early' conformation of the Escherichia coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome, as determined by cryo-EM.
Ban, Nenad, Boehringer, Daniel, Estrozi, Leandro F., Schaffitzel, Christiane, Shan, Shu-ou   +4 more
core   +1 more source

Bacterial Glycolipid Acting on Protein Transport Across Membranes

ChemBioChem, Volume 25, Issue 10, May 17, 2024.
In Escherichia coli inner membranes, diacylglycerol (DAG) and a glycolipid, named membrane protein integrase (MPIase), particularly influence membrane protein transport. This review explores the mechanisms of membrane protein integration mediated by these factors, and the methods and results of physicochemical analysis are presented.
Shoko Mori, Masafumi Shionyu, Keiko Shimamoto, Kaoru Nomura   +3 more
wiley   +1 more source

YidC and Oxa1 Form Dimeric Insertion Pores on the Translating Ribosome [PDF]

Molecular Cell, 2009
The YidC/Oxa1/Alb3 family of membrane proteins facilitates the insertion and assembly of membrane proteins in bacteria, mitochondria, and chloroplasts. Here we present the structures of both Escherichia coli YidC and Saccharomyces cerevisiae Oxa1 bound to E. coli ribosome nascent chain complexes determined by cryo-electron microscopy.
Kohler, Rebecca, Boehringer, Daniel, Greber, Basil, Bingel-Erlenmeyer, Rouven, Collinson, Ian, Schaffitzel, Christiane, Ban, Nenad   +6 more
openaire   +3 more sources

The correlation between traditional Chinese medicine constitution and prediabetes: a systematic review and meta-analysis

Frontiers in Endocrinology
ObjectivesThe aims of this study were to investigate the distribution of traditional Chinese medicine (TCM) constitution types in individuals with prediabetes and to identify high-risk constitutions, thereby providing an evidence-based foundation for the
Liqian Chen, Liqian Chen, Yun Wang, Yun Wang, Xinhui Xie, Xinhui Xie, Zhiyi Zhou, Zhiyi Zhou, Lu Xie, Lu Xie, Jiaxin Cai, Hao Li, Xinyu Zhang, Yijin Ke, Qingzi Li, Zhiqi Wu, Xiaoshan Zhao, Wenying Wang, Wenying Wang, Wenying Wang   +19 more
doaj   +1 more source

Comparative genomics of the proteostasis network in extreme acidophiles.

PLoS ONE, 2023
Extreme acidophiles thrive in harsh environments characterized by acidic pH, high concentrations of dissolved metals and high osmolarity. Most of these microorganisms are chemolithoautotrophs that obtain energy from low redox potential sources, such as ...
Katherin Izquierdo-Fiallo, Claudia Muñoz-Villagrán, Omar Orellana, Rachid Sjoberg, Gloria Levicán   +4 more
doaj   +1 more source