Results 111 to 120 of about 3,619 (189)

Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits

IUBMB Life, Volume 76, Issue 3, Page 125-139, March 2024.
Abstract The complexes mediating oxidative phosphorylation (OXPHOS) in the inner mitochondrial membrane consist of proteins encoded in the nuclear or the mitochondrial DNA. The mitochondrially encoded membrane proteins (mito‐MPs) represent the catalytic core of these complexes and follow complicated pathways for biogenesis.
Sung‐jun Jung, Sagar Sridhara, Martin Ott   +2 more
wiley   +1 more source

Sec translocon has an insertase-like function in addition to polypeptide conduction through the channel [version 1; peer review: 4 approved]

F1000Research, 2019
The Sec translocon provides a polypeptide-conducting channel, which is insulated from the hydrophobic lipidic environment of the membrane, for translocation of hydrophilic passenger polypeptides.
Koreaki Ito, Naomi Shimokawa-Chiba, Shinobu Chiba   +2 more
doaj   +1 more source

Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle.

PLoS Biology, 2020
Small membrane proteins represent a largely unexplored yet abundant class of proteins in pro- and eukaryotes. They essentially consist of a single transmembrane domain and are associated with stress response mechanisms in bacteria. How these proteins are
Ruth Steinberg, Andrea Origi, Ana Natriashvili, Pinku Sarmah, Mariya Licheva, Princess M Walker, Claudine Kraft, Stephen High, Joen Luirink, Wei Q Shi, Martin Helmstädter, Maximilian H Ulbrich, Hans-Georg Koch   +12 more
doaj   +1 more source

BrisSynBio:a BBSRC/EPSRC-funded Synthetic Biology Research Centre [PDF]

, 2016
BrisSynBio is the Bristol-based Biotechnology and Biological Sciences Research Council (BBSRC)/Engineering and Physical Sciences Research Council (EPSRC)-funded Synthetic Biology Research Centre. It is one of six such Centres in the U.K.
Race, Paul R, Sedgley, Kathleen R, Woolfson, Dek N   +2 more
core   +1 more source

Screening Marine Microbial Metabolites as Promising Inhibitors of Borrelia garinii: A Structural Docking Approach towards Developing Novel Lyme Disease Treatment

BioMed Research International, Volume 2024, Issue 1, 2024.
Lyme disease caused by the Borrelia species is a growing health concern in many parts of the world. Current treatments for the disease may have side effects, and there is also a need for new therapies that can selectively target the bacteria. Pathogens responsible for Lyme disease include B. burgdorferi, B. afzelii, and B. garinii.
Zarrin Basharat, Sadia Sattar, Ammar Abdulraheem Bahauddin, Abdulaziz K. Al Mouslem, Ghallab Alotaibi, Abdulaziz Alouffi   +5 more
wiley   +1 more source

Membrane insertion and topology of the TRanslocating chain-Associating Membrane protein (TRAM) [PDF]

, 2011
The translocating chain-associating membrane protein (TRAM) is a glycoprotein involved in the translocation of secreted proteins into the endoplasmic reticulum (ER) lumen and in the insertion of integral membrane proteins into the lipid bilayer.
Alder, Arthur E. Johnson, Bano-Polo, Cross, Dalbey, Do, Enquist, Görlich, Görlich, Hedin, Heinrich, Heinrich, Hessa, Hessa, Ismael Mingarro, Kanner, Krieg, Krieg, Krogh, Lerch-Bader, Luis Martínez-Gil, Martinez-Gil, Martinez-Gil, Martinez-Gil, Marçal Vilar, McCormick, Meacock, Nilsson, Nilsson, Nilsson, Orzaez, Saaf, Sauri, Sauri, Sauri, Silvia Tamborero, Skach, Thrift, Van den Berg, Voigt, von Heijne, Walter, Wilkinson, Yu   +43 more
core   +1 more source

Assignment of novel functions to Helicobacter pylori 26695’s genome [PDF]

, 2013
Helicobacter pylori is a pathogenic bacterium that colonizes the human epithelia, causing duodenal and gastric ulcers as well as gastric cancer. The genome of H. pylori 26695 has been sequenced and annotated.
Correia, Daniela M., Resende, T., Rocha, I.   +2 more
core   +1 more source

Functional Traits Co-Occurring with Mobile Genetic Elements in the Microbiome of the Atacama Desert [PDF]

, 2019
Mobile genetic elements (MGEs) play an essential role in bacterial adaptation and evolution. These elements are enriched within bacterial communities from extreme environments. However, very little is known if specific genes co-occur with MGEs in extreme
Airo, Alessandro, Schloter, Michael, Schulze-Makuch, Dirk, Sáenz, Johan S., Vestergaard, Gisle   +4 more
core   +1 more source

OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect

EMBO Molecular Medicine, 2018
OXA1, the mitochondrial member of the YidC/Alb3/Oxa1 membrane protein insertase family, is required for the assembly of oxidative phosphorylation complexes IV and V in yeast.
Kyle Thompson, Nicole Mai, Monika Oláhová, Filippo Scialó, Luke E Formosa, David A Stroud, Madeleine Garrett, Nichola Z Lax, Fiona M Robertson, Cristina Jou, Andres Nascimento, Carlos Ortez, Cecilia Jimenez‐Mallebrera, Steven A Hardy, Langping He, Garry K Brown, Paula Marttinen, Robert McFarland, Alberto Sanz, Brendan J Battersby, Penelope E Bonnen, Michael T Ryan, Zofia MA Chrzanowska‐Lightowlers, Robert N Lightowlers, Robert W Taylor   +24 more
doaj   +1 more source

Step size of the rotary proton motor in single FoF1-ATP synthase from a thermoalkaliphilic bacterium by DCO-ALEX FRET

, 2012
Thermophilic enzymes can operate at higher temperatures but show reduced activities at room temperature. They are in general more stable during preparation and, accordingly, are considered to be more rigid in structure.
Boersch, Michael, Cook, Gregory M., Ernst, Stefan, Hammann, Eva, Keis, Stefanie, Matthies, Doreen, Meier, Thomas, Zappe, Andrea   +7 more
core   +1 more source