Structural assembly of the bacterial essential interactome. [PDF]
Gómez Borrego J, Torrent Burgas M.
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Relevance of charged and polar amino acids for functionality of membrane toxin TisB. [PDF]
Leinberger FH, Berghoff BA.
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Identification and genome insights into <i>Pyrenochaeta nobilis</i>, a novel endophytic fungus isolated from <i>Astragalus membranaceus</i> with gray mold-control activity. [PDF]
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Roles of a Glycolipid MPIase in Sec-Independent Membrane Protein Insertion. [PDF]
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Embrace or resist: women and collective identification in Croatia and former Yugoslavia since WWII [PDF]
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YidC as a potential antibiotic target
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2023The membrane insertase YidC, is an essential bacterial component and functions in the folding and insertion of many membrane proteins during their biogenesis. It is a multispanning protein in the inner (cytoplasmic) membrane of Escherichia coli that binds its substrates in the "greasy slide" through hydrophobic interaction.
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YidC mediates membrane protein insertion in bacteria
Nature, 2000The basic machinery for the translocation of proteins into or across membranes is remarkably conserved from Escherichia coli to humans. In eukaryotes, proteins are inserted into the endoplasmic reticulum using the signal recognition particle (SRP) and the SRP receptor, as well as the integral membrane Sec61 trimeric complex (composed of alpha, beta and
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The evolutionarily conserved YidC/Oxa1/Alb3 family of proteins represents a unique membrane protein family that facilitates the insertion, folding, and assembly of a cohort of α‐helical membrane proteins in all kingdoms of life, yet its underlying mechanisms remain elusive. We report the crystal structures of the full‐length
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