Results 51 to 60 of about 3,619 (189)

Socializing, networking and development: a report from the second ‘Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis’ [PDF]

, 2012
In mid-June, the second Young Microbiologists Symposium took place under the broad title of ‘Microbe signalling, organization and pathogenesis’ on the picturesque campus of University College Cork, Ireland.
Barret, Brackman, Brown, Bush, Cascales, Corrigan, Costerton, Coulthurst, D'Autreaux, Davey, Delalez, Fazli, Gerlach, Hagan, Holland, Hood, Housden, Kleanthous, Kuchma, Kuchma, Kuchma, Lawley, Lebeer, Malone, McCarthy, Merritt, Murdoch, O'Connell Motherway, O'Connell Motherway, O'Toole, Porter, Ramsay, Ramsay, Rigel, Roberts, Ryan, Ryan, Ryan, Ryan, Ryan, Schwarz, Sharma, Shioya, Smith, Thompson, Twomey, Waters, Yang, Youle   +48 more
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Identification of Oxa1 Homologs Operating in the Eukaryotic Endoplasmic Reticulum

Cell Reports, 2017
Members of the evolutionarily conserved Oxa1/Alb3/YidC family mediate membrane protein biogenesis at the mitochondrial inner membrane, chloroplast thylakoid membrane, and bacterial plasma membrane, respectively.
S. Andrei Anghel, Philip T. McGilvray, Ramanujan S. Hegde, Robert J. Keenan   +3 more
doaj   +1 more source

YidC: Evaluating the Importance of the Native Environment [PDF]

Structure, 2018
In this issue of Structure, Baker et al. (2018) take advantage of recent technological breakthroughs in solid-state NMR spectroscopy and electron cryogenic tomography to characterize structural and functional differences between reconstituted YidC in E. coli lipids and YidC as overexpressed in the E. coli inner cellular membrane.
openaire   +2 more sources

YidC/Oxa1p/Alb3: evolutionarily conserved mediators of membrane protein assembly [PDF]

FEBS Letters, 2001
This review focuses on a novel, evolutionarily conserved mediator of membrane protein assembly in bacteria, mitochondria and chloroplasts. This factor is designated YidC in Escherichia coli, and is localized in the inner membrane. YidC is homologous to Oxa1p in the mitochondrial inner membrane and Alb3 in the chloroplast thylakoid membrane, but does ...
Luirink, Joen, Samuelsson, Tore, de Gier, Jan-Willem   +2 more
openaire   +2 more sources

Escherichia coli Can Adapt Its Protein Translocation Machinery for Enhanced Periplasmic Recombinant Protein Production

Frontiers in Bioengineering and Biotechnology, 2020
Recently, we engineered a tunable rhamnose promoter-based setup for the production of recombinant proteins in E. coli. This setup enabled us to show that being able to precisely set the production rate of a secretory recombinant protein is critical to ...
Alexandros Karyolaimos, Katarzyna Magdalena Dolata, Minia Antelo-Varela, Anna Mestre Borras, Rageia Elfageih, Susanne Sievers, Dörte Becher, Katharina Riedel, Jan-Willem de Gier   +8 more
doaj   +1 more source

mRNA targeting eliminates the need for the signal recognition particle during membrane protein insertion in bacteria

Cell Reports, 2023
Summary: Signal-sequence-dependent protein targeting is essential for the spatiotemporal organization of eukaryotic and prokaryotic cells and is facilitated by dedicated protein targeting factors such as the signal recognition particle (SRP).
Pinku Sarmah, Wenkang Shang, Andrea Origi, Mariya Licheva, Claudine Kraft, Maximilian Ulbrich, Elisabeth Lichtenberg, Annegret Wilde, Hans-Georg Koch   +8 more
doaj   +1 more source

Targeting, Insertion, and Localization of Escherichia coli YidC

Journal of Biological Chemistry, 2002
YidC was recently shown to play an important role in the assembly of inner membrane proteins (IMPs) both in conjunction with and separate from the Sec-translocon. Little is known about the biogenesis and structural and functional properties of YidC, itself a polytopic IMP. Here we analyze the targeting and membrane integration of YidC using in vivo and
Malene L, Urbanus, Linda, Fröderberg, David, Drew, Petra, Björk, Jan-Willem L, de Gier, Josef, Brunner, Bauke, Oudega, Joen, Luirink   +7 more
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Regulatory mechanisms of exopolysaccharide synthesis and biofilm formation in Streptococcus mutans

Journal of Oral Microbiology, 2023
Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial infection affecting almost every age group and every geographical region.
Ting Zheng, Meiling Jing, Tao Gong, Jiangchuan Yan, Xiaowan Wang, Mai Xu, Xuedong Zhou, Jumei Zeng, Yuqing Li   +8 more
doaj   +1 more source

Post-translational membrane insertion of an endogenous YidC substrate

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013
Membrane protein insertion is controlled by proteinaceous factors embedded in the lipid bilayer. Bacterial inner membrane proteins utilise the Sec translocon as the major facilitator of insertion; however some proteins are Sec independent and instead require only YidC. A common feature of YidC substrates is the exposure of a signal anchor sequence when
Robinson, Philip J., Woolhead, Cheryl A.
openaire   +2 more sources

A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways [PDF]

, 2017
The majority of multi-spanning membrane proteins are co-translationally inserted into the bilayer by the Sec pathway. An important subset of membrane proteins have globular, cofactor-containing extracytoplasmic domains requiring the dual action of the co-
Andersson, Bachmann, Bageshwar, Baniulis, Bartolomé, Berks, Bernhardt, Blaudeck, Bogdanov, Bogsch, Brokx, Brondijk, Caldelari, Casadaban, Cole, Collinson, Cooley, Cristóbal, Cymer, Dalbey, De Buck, Elofsson, Gennaris, Goder, Guzman, Hatzixanthis, Hedin, Heijne, Hessa, Hessa, Hopkins, Inouye, Ize, Ize, Jack, Jack, James, Jormakka, Keller, Kern, Koch, Kreutzenbeck, Krogh, Kudva, Lehr, Li, Liu, Lowry, Ma, Monteferrante, Musser, Nilsson, Ojemalm, Palmer, Puigbò, Rose, Sachelaru, Samuelson, Schneider, Scotti, Shanmugham, Stanley, Stanley, Summers, Tsirigos, Tsirigos, Tullman-Ercek, Ulbrandt, Urbanus, Virkki, von Heijne, Wahlberg, Wallin, Wexler, White, White, Zhu   +76 more
core   +3 more sources