Results 201 to 210 of about 583,000 (268)

Editorial: Harnessing resilient flora for maximized crop efficiency and stress tolerance. [PDF]

Front Plant Sci
Bosamia TC, Barbadikar KM, Nawade B, Saripalli G.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Targeting Myostatin for Sustainable Meat Production: Insights From Multiple Species. [PDF]

Anim Genet
Santomassimo C, Perini F, Colombi D, Bettini S, Trombetta MF, Pasquini M, Ceccobelli S, Haruna IL, Patel K, Lasagna E.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Galactooligosaccharides Based on β-Galactosidase-Catalyzed Synthesis: Function, Biosynthesis and Optimization Strategy. [PDF]

Foods
Tao B, Chen Y, He R, Huang T, Liang S, Chen H, Rao X, Tang X, Jiang J.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Yield and nitrogen use efficiency in optimized oat-common vetch mixtures on the Qinghai-Tibet plateau. [PDF]

Front Plant Sci
Bao M, Wang Z, Yan M, Zhang Y, Qin Y.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Applications and mechanisms of biochar-mycorrhizal synergies in agriculture based on systematic review. [PDF]

PeerJ
Setyawan HY, Widyastuti E, Sugiarto Y, Sunyoto NMS, Ulandari D, Dewi J, Choirun AU, Arwani M, Okoye C.   +8 more
europepmc   +1 more source

Harnessing artificial intelligence in plant breeding: innovations in digital phenotyping and breeding methodologies. [PDF]

Theor Appl Genet
Aggarwal N, Rathore M, Jan F, Sharma D, Kumar S, Thudi M, Jighly A, Varshney RK, Mir RR.   +8 more
europepmc   +1 more source