Results 161 to 170 of about 6,883,757 (381)
Germline Engineering: Whose Right? [PDF]
Professor Cohen presents and analyzes a taxonomy of the potential harms of human genetic “germline engineering.” Germline engineering is the process of “artificially” and purposefully changing the genes of an organism such that when it procreates the ...
Lloyd Cohen
core
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
A discontinuous Galerkin method for cohesive zone modelling [PDF]
arXiv, 2015 We propose a discontinuous finite element method for small strain elasticity allowing for cohesive zone modeling. The method yields a seamless transition between the discontinuous Galerkin method and classical cohesive zone modeling. Some relevant numerical examples are presented.
arxiv
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
458. Molecular Engineering of Adeno-Associated Virus Yields a Novel Variant with Efficient Intravitreal Transduction of Müller Cells [PDF]
, 2009 R. R. Klimczak +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Towards Reverse Engineering Reversible Logic [PDF]
arXiv, 2017 Reversible logic has two main properties. First, the number of inputs is equal to the number of outputs. Second, it implements a one-to-one mapping; i.e., one can reconstruct the inputs from the outputs. These properties enable its applications in building quantum computing architectures.
arxiv
Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations [PDF]
, 2010 Debra Toiber +5 more
openalex +1 more source
A flight instrumentation system for acquisition of atmospheric turbulence data [PDF]
A flight instrumentation system for the acquisition of atmospheric turbulence data is described. Airflow direction transducers and an impact pressure transducer are the primary instruments for measuring vertical and lateral gust velocity, and a sensitive
Meissner, C. W., Jr.
core +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source