Recent advances in keratinase production via protein engineering, breeding, and fermentation
The gene editing and synthetic biological tools have led to the implementation of diverse metabolic engineering approaches to enhance the production of specific enzymes. Microbial keratinases can convert keratin wastes into valuable compounds for mankind.
Ali Raza Ishaq+4 more
doaj
Regional Effects of Enzymatic Digestion on Knee Meniscus Cell Yield and Phenotype for Tissue Engineering [PDF]
Johannah Sanchez‐Adams+1 more
openalex +1 more source
Fluid dynamic-based Engineering design of a Full-Scale Device for the improvement of Extra Virgin Olive Oil Yield and Quality by means of Combined Acoustic Cavitation and Thermal Conditioning [PDF]
Riccardo Amirante+5 more
openalex +1 more source
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source
Enhancing the efficiency of quantum measurement-based engines with entangling measurements [PDF]
We study the impact of entangling measurements on the efficiency of quantum measurement- based engines. We first show that for engines comprising many subsystems their efficiency can be enhanced by performing entangling measurements, as opposed to local measurements over each subsystem.
arxiv
Rational Metabolic Engineering of Escherichia Coli for High-yield L-serine Production [PDF]
Chenyang Wang+8 more
openalex +1 more source
A predictive model for failure properties of thermoset resins [PDF]
A predictive model for the three-dimensional failure behavior of engineering polymers has been developed in a recent NASA-sponsored research program.
Bowles, Kenneth J., Caruthers, James M.
core +1 more source
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou+11 more
wiley +1 more source
Yield and Buckling Stress Limits in Topology Optimization of Multiscale Structures [PDF]
This study presents an extension of multiscale topology optimization by integrating both yield stress and local/global buckling considerations into the design process. Building upon established multiscale methodologies, we develop a new framework incorporating yield stress limits either as constraints or objectives alongside previously established ...
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source