Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Synthesis of polylactic acid/Henna polymer composite and its application in optimizing drilling fluid rheology and filtration performance. [PDF]
Hsu CY +9 more
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Machine learning framework for predicting the shear capacity of demountable bolted connectors in composite beams. [PDF]
Saleh AI +4 more
europepmc +1 more source
Integration of an ultra-strong poly(lactic-co-glycolic acid) (PLGA) knitted mesh into a thermally induced phase separation (TIPS) PLGA porous structure to yield a thin biphasic scaffold suitable for dermal tissue engineering [PDF]
Eamonn McKenna +3 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Synergistic effects on biofuel yields and heating value during co-pyrolysis of sewage sludge and sugarcane residue under different blend ratios. [PDF]
Kamesh MR +8 more
europepmc +1 more source
ENGINEERING PARAMETER PERFORATED PIPES SYSTEM AFFEECTIN ON WATER IRRIGATION EFFICIENCY OF THE YIELD WHEAT CROP. [PDF]
Sher Shah Hassan +2 more
openalex +1 more source

