Results 221 to 230 of about 6,436,199 (299)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Toward Rational Design of Precision-Fermented Milk Proteins: Integrating Cross-Species Selection, Post-Translational Modification, and AI Optimization. [PDF]

Compr Rev Food Sci Food Saf
Guo Z, Ye K, Shi Z, Li J, Zhang S, Li B, Liu F.   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Correction: Effects of different bio-organic fertilizers on agronomic traits, yield, and dry matter accumulation of fresh-eating corn in arid and saline soils of Xinjiang: a single-site field experiment. [PDF]

Front Plant Sci
Cui Y, Tang Y, Du Y, Ding W, Ren H, Jia Y, Shi X, Wang W, Ji S, Ma Y.   +9 more
europepmc   +1 more source

Rigidity, Yield Value and pF in Soil Engineering

Transactions of The Japanese Society of Irrigation, Drainage and Reclamation Engineering, 1965
YASUTOMI, Rokuro, TAKENAKA, Hajime, SUDO, Seiji   +2 more
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Enhancing Enzyme Activity With Mutation Combinations Guided by Few-Shot Learning and Causal Inference. [PDF]

Angew Chem Int Ed Engl
Guo L, Yan X, Lu Y, Nie S, Ge M, Li Y, Li W, Zhang X, Liang D, Zhao Y, Tan H, Chen X, Fan S, Tang Y, Qiao J, Tian B.   +15 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

CRISPR-Cas technologies for precision genome editing in plants: advances, applications, and future perspectives. [PDF]

Front Plant Sci
Riaz Ahmed S, Khan J, Ijaz I, Ali Z, Rasul I, Aslam M, Ud-Din N, Liu Y, Tariq MS, Skalicky M, Tan DKY.   +10 more
europepmc   +1 more source