Results 201 to 210 of about 1,794,891 (330)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Advanced metabolic engineering strategies for increasing artemisinin yield in Artemisia annua L. [PDF]

Yongpeng Li, Yinkai Yang, Ling Li, Kexuan Tang, Xiaolong Hao, Guoyin Kai   +5 more
openalex   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Author Correction: Optimized protein-water interactions and torsional refinements yield balanced atomistic protein force fields. [PDF]

Nat Commun
Phan TM, Mohanty P, Mittal J.
europepmc   +1 more source

MOESM3 of High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii

, 2016
Veerle E. T. Maervoet, Sofie De Maeseneire, Fatma Avci, Joeri Beauprez, Wim Soetaert, Marjan De Mey   +5 more
openalex   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Correction: Bio-organic fertilizers modulate the rhizosphere bacterial community to improve plant yield in reclaimed soil. [PDF]

Front Plant Sci
Qiao C, Yang J, Shao Q, Fu J, Zheng X, Zhao J, Ren L, Wu W, Wang J.   +8 more
europepmc   +1 more source

458. Molecular Engineering of Adeno-Associated Virus Yields a Novel Variant with Efficient Intravitreal Transduction of Müller Cells [PDF]

, 2009

openalex   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction of <i>N</i>-Alkylated α-Aminoketones. [PDF]

J Am Chem Soc
Qin ZY, Li ZQ, Zhang C, Heise JL, Mao R, Wu SJ, Houk KN, Goddard Iii WA, Arnold FH.   +8 more
europepmc   +1 more source