Results 81 to 90 of about 6,883,757 (381)
Analysis-of-marginal-Tail-Means (ATM): a robust method for discrete black-box optimization
, 2018 We present a new method, called Analysis-of-marginal-Tail-Means (ATM), for effective robust optimization of discrete black-box problems. ATM has important applications to many real-world engineering problems (e.g., manufacturing optimization, product ...
Mak, Simon, Wu, C. F. Jeff
core +2 more sources
Design degrees of freedom and mechanisms for complexity [PDF]
, 2002 We develop a discrete spectrum of percolation forest fire models characterized by increasing design degrees of freedom (DDOF’s). The DDOF’s are tuned to optimize the yield of trees after a single spark.
Carlson, J. M. +2 more
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Astaxanthin overproduction in yeast by strain engineering and new gene target uncovering
Biotechnology for Biofuels, 2018 Background Astaxanthin is a natural carotenoid pigment with tremendous antioxidant activity and great commercial value. Microbial production of astaxanthin via metabolic engineering has become a promising alternative.
Jin Jin +8 more
doaj +1 more source
The Need, Benefits, and Demonstration of a Minimization Principle for Excited States
, 2015 It is shown that the standard methods of computing excited states in truncated spaces must yield wave functions that, beyond truncation, are in principle veered away from the exact, and a remedy is demonstrated via a presented functional, F$_n$, obeying ...
Bacalis, Naoum C.
core +1 more source
From fly-by-wire to drive-by-wire: Safety implications of automation in vehicles [PDF]
, 1996 The purpose of this paper is to critically review the current trend in automobile engineering toward automation of many of the functions previously performed by the driver.
Anderson +31 more
core +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Ribosome Pool Engineering Increases Protein Biosynthesis Yields
ACS Central ScienceThe biosynthetic capability of the bacterial ribosome motivates efforts to understand and harness sequence-optimized versions for synthetic biology. However, functional differences between natively occurring ribosomal RNA (rRNA) operon sequences remain poorly characterized. Here, we use an in vitro ribosome synthesis and translation platform to measure
Camila Kofman +3 more
openaire +3 more sources
Developing Genetic Engineering Techniques for Control of Seed Size and Yield
International Journal of Molecular Sciences, 2022 Many signaling pathways regulate seed size through the development of endosperm and maternal tissues, which ultimately results in a range of variations in seed size or weight. Seed size can be determined through the development of zygotic tissues (endosperm and embryo) and maternal ovules. In addition, in some species such as rice, seed size is largely
Alam, Intikhab +4 more
openaire +2 more sources
Microorganisms, 2021 We previously constructed a Saccharomyces cerevisiae carotenoid producer BL03-D-4 which produced much more carotenoid in YPM (modified YPD) media than YPD media.
Buli Su +3 more
doaj +1 more source