Results 151 to 160 of about 4,436,723 (262)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Grain Yield Adaptability and Stability of Quinoa (Chenopodium quinoa Willd.) Genotypes Using Different Stability Indices

Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī
Quinoa is known as a suitable plant in adverse environmental conditions due to its desirable nutritional value and high production potential such a country like Iran, which has a climate diversity, it will create food security, increase farmers ...
Maryam Etaati, Mohammad Reza Ardakani, Mahmoud Bagheri, Farzad Paknejad, Farid Golzardi   +4 more
doaj  

The yield spread and GDP growth - Time Varying Leading Properties and the Role of Monetary Policy [PDF]

The yield spread is a well documented leading indicator of GDP growth. Estrella (2005) proposes a model to explain this relationship. Within the model, the leading properties of the yield spread are determined by the monetary policy. Accordingly, changes
Hogrefe, Jens
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Finlay-Wilkinson random regression for yield and yield stability prediction in cereals. [PDF]

Plant Genome
Sandro P, Blancon J, Neyhart J, Dawson J, Gutiérrez L.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Multi-model assessment of yield stability in lentil across multi-environments. [PDF]

PLoS One
Asghar MJ, Ghaffar M, Shahid M, Akhtar KP, Hameed A, Tabasum A, Rabbani G, Javed U, Shahbaz MU, Kamran M, Ehtisham-Ul-Haq M.   +10 more
europepmc   +1 more source

Assessment of Yield Stability in Sorghum

, 2007
Sorghum (Sorghum bicolor L. (Moench)) is the third major cereal crop in Ethiopia in terms of area and production next to tef (Eragrostis tef) and maize (Zea mays). It is the major crop in drought stressed lowland areas that cover 66 % of the total arable
Asfaw Adugna
core