Results 171 to 180 of about 7,911,045 (336)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular mechanisms of stress resistance in sorghum: Implications for crop improvement strategies
Journal of Integrative AgricultureAbiotic stresses, such as drought, salt, extreme temperatures, and heavy metal pollution, are the main environmental factors that limit crop growth and yield.
Hongxiang Zheng +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
International Journal of Plant BiologyPurple corn (Zea mays L.) is a nutraceutical crop of increasing economic importance in Peru, yet its productivity is highly influenced by genotype × environment (G × E) interactions across heterogeneous agro-ecological zones.
Gilberto Garcia +10 more
doaj +1 more source
RISK ANALYSIS OF CROPPING SYSTEMS USING EXPERIMENTAL CROPPING SYSTEM-FERTILIZER DATA [PDF]
Using 11 years of experimental crop yields by cropping systems and fertilizer level, a MOTAD frontier was developed. This analysis allowed yield, cost, and stability interactions arising from crop sequences to be implicitly included. Target-MOTAD, Safety-
Atwood, Joseph A. +3 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
DP202216 maize hybrids shift upper limit of C and N partitioning to grain
Frontiers in Plant ScienceIncreasing both harvest index (HI) and nitrogen (N) harvest index (NHI) is a promising approach for improving the effective use of resources in grain crops.
Francisco Palmero +8 more
doaj +1 more source
Use of satellite data and modeling to assess the influence of stratospheric processes on the troposphere [PDF]
Over the past forty years, numerous linear stability studies have been performed in order to explain the origin and structure of observed waves in the atmosphere.
Nathan, Terrence
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source