Bridging Breeds: Transcriptomic Insights into Immune Traits of Yili, Thoroughbred, and Kazakh Horses [PDF]
LifeBackground: Studying the genetic characteristics and molecular mechanisms of immune regulation in horses is of great significance for protecting their genetic resources, improving breeding strategies, and enhancing their disease resistance, thereby ...
Tongliang Wang +7 more
doaj +4 more sources
Differential Energy Metabolism in Skeletal Muscle Tissues of Yili Horses Based on Targeted Metabolomics and Transcriptomics Analysis [PDF]
BiologySkeletal muscle is the largest organ system in mammals. To investigate the differences in energy metabolism across various skeletal muscles in Yili horses, this study examined muscle fiber type distributions through immunohistochemical staining of ...
Xueyan Li +6 more
doaj +5 more sources
Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race [PDF]
Frontiers in GeneticsEquine athletic performance is modulated by both genetic and epigenetic mechanisms. As dynamic regulators of gene expression, MicroRNAs (miRNAs) play a central role in the physiological response to exercise-induced stress18. This study focused on the top
Shikun Ma +10 more
doaj +4 more sources
The Impact of the Competition on miRNA, Proteins, and Metabolites in the Blood Exosomes of the <i>Yili</i> Horse. [PDF]
Genes (Basel)Purpose: Horse racing may cause stress-induced physiological changes and tissue damage in horses, but the changes in miRNA expression, protein expression, and metabolic substances in the plasma exosomes of the Yili horse after racing are still unclear ...
Yuan X +9 more
europepmc +4 more sources
Untargeted Sweat Metabolomics and Targeted Plasma Amino Acid Profiling Reveal Dynamic Metabolic Remodeling During Conditioning in Yili Horses [PDF]
BiologyTraining induces sweat morphology changes in horses from muddy sweat (MS) to foamy sweat (FS) and clear sweat (CS), reflecting physiological adaptation.
Yuheng Xue +8 more
doaj +4 more sources
Blood-Based Whole-Genome Methylation Analysis of Yili Horses Pre- and Post-Racing
AnimalsThis study aims to analyze the whole-genome DNA methylation differences in Yili horses before and after racing, with the goal of identifying differentially methylated genes associated with racing performance and exploring the epigenetic mechanisms ...
Wanlu Ren, Lüling Li, Zexu Li
exaly +5 more sources
Genome-Wide DNA Methylation Analysis of Performance Variation in the 5000-m Speed Race of Yili Horses [PDF]
AnimalsWhole-genome bisulfite sequencing (WGBS) was employed in this article to map blood DNA methylation profiles at single-base resolution in Yili horses before a 5000 m speed race, with comparative analysis of epigenetic differences between the ‘elite group’
Dehaxi Shan +9 more
doaj +5 more sources
Multi-Omics Deciphers Divergent Mechanisms in Differentially Cardiac-Remodeled Yili Horses Under Conditions of Equivalent Power Output [PDF]
AnimalsExercise performance is a critical trait for evaluating the economic and breeding value of working and athletic horses, with cardiac structure and function serving as essential physiological determinants of athletic capacity.
Tongliang Wang +8 more
doaj +5 more sources
Frontiers in Veterinary ScienceThe objective of this study was to examine the effects of supplemental β-alanine feeding on the athletic performance of Yili horses involved in speed racing, focusing on alterations in plasma free amino acid patterns pre and post exercise.
Yuhui Ma
exaly +5 more sources
Differential Metabolomics and Cardiac Function in Trained vs. Untrained Yili Performance Horses [PDF]
AnimalsThis study aimed to investigate the effects of training on cardiac structure and function, as well as plasma metabolite profiles in horses, in order to uncover the molecular regulatory mechanisms and cardiac remodeling under long-term exercise. We hypothesize that long-term standardized training induces physiological cardiac remodeling and differential
Xinkui Yao, Wanlu Ren, Tongliang Wang
exaly +4 more sources