Combined Analysis of the Transcriptome and Metabolome at Different Tissue Glycogen Levels in Yili Horses [PDF]
AnimalsThis study aimed to investigate the relationship between genes and metabolites involved in glycogen metabolism across different tissues of Yili mares using joint transcriptomic and metabolomic analyses.
Xueyan Li +6 more
doaj +5 more sources
ATAC-seq and RNA-seq reveal key genes and pathways regulating lactation in the mammary gland of Yili horses [PDF]
BMC GenomicsBackground Mammary gland development and lactation are dynamic biological processes governed by coordinated changes in chromatin accessibility and gene expression.
Lingling Liu +6 more
doaj +3 more sources
Integrative Metabolomic and Echocardiographic Profiling Reveals Metabolic–Cardiac Structural Coupling in Yili Horses During Incremental Exercise [PDF]
AnimalsThis study integrated echocardiography with widely targeted metabolomics to decipher how plasma metabolic dynamics couple with cardiac geometry in Yili horses during incremental treadmill exercise. Nine speed-type horses underwent a graded exercise test (
Xiaokang Chang +9 more
doaj +3 more sources
Blood-Based Whole-Genome Methylation Analysis of Yili Horses Pre- and Post-Racing
AnimalsThis study aims to analyze the whole-genome DNA methylation differences in Yili horses before and after racing, with the goal of identifying differentially methylated genes associated with racing performance and exploring the epigenetic mechanisms ...
Wanlu Ren, Lüling Li, Zexu Li
exaly +5 more sources
The Impact of the Competition on miRNA, Proteins, and Metabolites in the Blood Exosomes of the <i>Yili</i> Horse. [PDF]
Genes (Basel)Purpose: Horse racing may cause stress-induced physiological changes and tissue damage in horses, but the changes in miRNA expression, protein expression, and metabolic substances in the plasma exosomes of the Yili horse after racing are still unclear.
Yuan X +9 more
europepmc +4 more sources
Genome-Wide DNA Methylation Analysis of Performance Variation in the 5000-m Speed Race of Yili Horses [PDF]
AnimalsWhole-genome bisulfite sequencing (WGBS) was employed in this article to map blood DNA methylation profiles at single-base resolution in Yili horses before a 5000 m speed race, with comparative analysis of epigenetic differences between the ‘elite group’
Dehaxi Shan +9 more
doaj +5 more sources
Multi-Omics Deciphers Divergent Mechanisms in Differentially Cardiac-Remodeled Yili Horses Under Conditions of Equivalent Power Output [PDF]
AnimalsExercise performance is a critical trait for evaluating the economic and breeding value of working and athletic horses, with cardiac structure and function serving as essential physiological determinants of athletic capacity.
Tongliang Wang +8 more
doaj +5 more sources
Frontiers in Veterinary ScienceThe objective of this study was to examine the effects of supplemental β-alanine feeding on the athletic performance of Yili horses involved in speed racing, focusing on alterations in plasma free amino acid patterns pre and post exercise.
Haifeng Deng
exaly +5 more sources
Effects of Different Stages of Training on the Intestinal Microbes of Yili Horses Analyzed Using Metagenomics [PDF]
GenesObjectives: The aim of this study was to investigate the effects of different stages of training on the intestinal microbial abundance of Yili horses. Methods: Ten Yili horses, all aged 2 years old and weighing 305 ± 20 kg, were selected and divided into a training group and an untrained group. The training group performed riding training 6 days a week,
Sun YF +10 more
exaly +4 more sources
H3K4me3 CUT&Tag and Transcriptome Analysis Reveal the Epigenetic Regulatory Landscape in Mammary Gland Tissues of Yili Horses at Different Lactation Stages [PDF]
AnimalsH3K4me3, a well-established histone modification associated with active promoters, plays a critical role in orchestrating gene expression programs that govern mammary gland development and lactation.
Lingling Liu +4 more
doaj +2 more sources