Results 71 to 80 of about 111,326,060 (152)

Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53 [PDF]

open access: yesThe Journal of Immunology, 2016
Abstract Yin Yang 1 (YY1) is a zinc finger protein that functions as a transcriptional activator or repressor and participates in multiple biological processes, including development and tumorigenesis. To investigate the role of YY1 in developing T cells, we used mouse models that depleted YY1 at two distinct stages of thymocyte ...
Liang Chen   +3 more
openaire   +2 more sources

Yin-Yang In Epistemology [PDF]

open access: yes
In this dissertation, I propose a novel model to analyze the process of inquiry and deliberation in terms of an updated concept of yin-yang in Chinese philosophy.
Ma, Zhiyao
core   +3 more sources

Bioinformatics Analysis of the Expression and Prognostic Significance of Transcription Factor YY1 in Gastric Cancer

open access: yesCancer Reports
Background Emerging evidence indicates that the transcription factor Yin Yang 1 (YY1) plays a critical role in the carcinogenesis and progression of various human malignancies.
Wenliang Chen   +5 more
doaj   +1 more source

The novel role of Yin Yang 1 in acute rejection of liver allografts through activation of dendritic cells

open access: yesFrontiers in Immunology
IntroductionAcute rejection is a critical complication after liver transplantation, contributing significantly to transplant dysfunction and recipient mortality.
Yi Chen   +10 more
doaj   +1 more source

Yin Yang 1 intronic binding sequences and splicing elicit intron-mediated enhancement of ubiquitin C gene expression. [PDF]

open access: yesPLoS ONE, 2013
In a number of organisms, introns affect expression of the gene in which they are contained. Our previous studies revealed that the 5'-UTR intron of human ubiquitin C (UbC) gene is responsible for the boost of reporter gene expression and is able to bind,
Marzia Bianchi   +5 more
doaj   +1 more source

Yin-yang 1 activates the c-myc promoter. [PDF]

open access: yesMolecular and Cellular Biology, 1993
Previous studies on the murine c-myc promoter demonstrated that a ubiquitously present protein, common factor 1 (CF1), bound at two sites located -260 and -390 bp from the P1 transcription start site. CF1 has been purified to near homogeneity and shown to be identical to the zinc finger protein Yin-yang 1 (YY1) as judged by similarity of molecular ...
K J, Riggs   +6 more
openaire   +2 more sources

Is Yin-Yang superior for paradox research? [PDF]

open access: yes
PurposeThe paper debunks Peter P. Li’s assertion that Yin-Yang is superior to any other cognitive frames or logical systems for paradox research. The purpose of this paper is to alert the Chinese indigenous management researchers to the danger of Chinese
Li X, Xie P, Worm V
core   +2 more sources

Yin Yang 1 (YY1) as a Central Node in Drug Resistance Pathways: Potential for Combination Strategies in Cancer Therapy

open access: yesBiomolecules
Tumor drug resistance, a major cause of treatment failure, involves complex multi-gene networks, remodeling of signaling pathways, and interactions with the tumor microenvironment.
Zhiyan Li   +4 more
doaj   +1 more source

Treatment of Granulomatous Mastitis with Half-Yin and Half-Yang Syndrome

open access: yes, 2023
Granulomatous mastitis (GM) is a refractory chronic mastitis, which belongs to the category of “acne mammary abscess” and “ulcer” in Traditional Chinese External Medicine.
Huiduo Zhao   +3 more
core   +1 more source

Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Shibali Das, Shabaana Khader
doaj   +1 more source

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