Results 151 to 160 of about 38,911 (296)

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, Volume 14, Issue 1, Page 210-227, January 2026.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Advances in non‐germ cell tumours of the testis: focus on new molecular developments in sex cord‐stromal tumours

open access: yesHistopathology, Volume 88, Issue 1, Page 230-251, January 2026.
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley   +1 more source

Primary Pineal Yolk Sac Tumor: Ultrastructural and Immunohistochemical Features

open access: bronze, 1986
Shunji Nishio   +4 more
openalex   +2 more sources

GCT-45. YOLK SAC TUMOR IN THE CEREBELLAR VERMIS - A CASE REPORT [PDF]

open access: hybrid, 2020
Saori Otake   +7 more
openalex   +1 more source

Low‐grade glial neoplasms of germ cell origin may represent maturation of embryonic‐type neuroectodermal elements

open access: yesHistopathology, Volume 88, Issue 2, Page 503-514, January 2026.
Our results support that low grade glial tumours of germ cell origin (LGGTs) represent a phenomenon of maturation (either spontaneous or induced by therapy) of embryonic‐type neuroectoderm, being possibly equivalent to teratoma from a biological perspective.
João Lobo   +10 more
wiley   +1 more source

Molecular pathology of testicular germ cell tumours: an update for practicing pathologists

open access: yesHistopathology, Volume 88, Issue 1, Page 214-229, January 2026.
Molecular testing for isochromosome 12p is usually only necessary in difficult cases that encompass metastases or recurrent diseases including somatic‐type malignancies. So far, no breaking progress has been made in the field of targeted therapy as TGCTs only rarely show targetable molecular alterations.
Alexander Fichtner   +3 more
wiley   +1 more source

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