Results 51 to 60 of about 30,193 (222)

Ultrasonic misdiagnosis of giant pediatric testicular yolk sac tumor: A case report and literature review

Frontiers in Pediatrics, 2022
BackgroundYolk sac tumor is the most common malignant nonseminomatous germ-cell tumor in children characterized by elevated level of α-fetoprotein (AFP), accounting for 70%–80% of all cases. However, giant yolk sac tumors that involve the entire testicle
Zilong Wang, Fuding Lu, Changze Song, Xinkun Wang, Naifa Li, Jiawen Zhai, Baohong Jiang, Jianpeng Yuan, Zheng Yang, Xujun Xuan, Xujun Xuan   +10 more
doaj   +1 more source

AMHR2 mutation in persistent Müllerian duct syndrome: A case of transverse testicular ectopia

UroPrecision, EarlyView.
Abstract Backgroud Persistent Müllerian duct syndrome (PMDS) is a rare condition characterized by the persistence of Müllerian duct structures in genotypic and phenotypic males. Case Presentation We present the case of a 4‐month‐old male with PMDS who presented with transverse testicular ectopia. The patient underwent diagnostic laparoscopic orchiopexy
Hangcheng Fu, Weijing Huang, Jeffrey T. White   +2 more
wiley   +1 more source

Epidermal growth factor receptor is a marker for syncytiotrophoblastic cells in testicular germ cell tumors [PDF]

, 2018
The epidermal growth factor receptor (EGFR) has been implicated in the pathogenesis, therapy and prognosis of various tumor types. The aim of this study was to investigate EGFR expression in a large series of testicular germ cell tumors (TGCTs).
Hechelhammer, Lukas, Heitz, Philipp, Jochum, Wolfram, Odermatt, Bernhard, Störkel, Stephan   +4 more
core  

Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Extragonadal germ cell tumors (EGCTs) are rare, with limited prospective data to guide treatment or inform prognosis. Incidence and treatment patterns of EGCT in Australia reflect international data and practices. Compared to testicular primaries, the prognosis of EGCT is poor, especially for primary mediastinal non‐seminoma.
Kar Ven Cavan Chow, Ciara Conduit, Sophie O'Haire, Anna Kuchel, Shirley Wong, Peter Grimison, Andrew Weickhardt, Ganes Pranavan, James Lynam, Patricia Bastick, Jeffrey Goh, Shomik Sengupta, Annabel Smith, Elizabeth Liow, David Campbell, Ming Wong, Kristina Zlatic, Peter Gibbs, Ben Tran, Chun Loo Gan   +19 more
wiley   +1 more source

A Malignant Yolk Sac Tumor of the Ovary Presenting as Adnexal Torsion in a Child

Swiss Journal of Radiology and Nuclear Medicine
Introduction: Malignant yolk sac tumor is a rare ovarian neoplasm with peak incidence in young women. Its occurrence in children less than 10 years old is extremely uncommon.
Kabhilan A K, Ebinesh Arulnathan, Karunakaran N, Padma S, Praislin Gideon   +4 more
doaj   +1 more source

Endometrioid like yolk sac tumor of the testis with small teratomatous foci: A case report and review of the literature

Indian Journal of Pathology and Microbiology, 2015
I have reported a case of endometrioid like yolk sac tumor of the testis in a 20-year-old boy. Endometrioid like yolk sac tumor is a rare tumor. A few cases have been reported in ovary. In case of male, a case of pure glandular endometrioid like yolk sac
Prabir Hazarika
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Ovarian Yolk Sac Tumors: Is Fertility Preservation Possible?

Advanced Biomedical Research
Yolk sac tumors make up 14% to 20% of all malignant ovarian germ cell tumors. Serum alpha-fetoprotein (AFP) levels are elevated in a significant number of patients and are useful for monitoring the response to treatment and for post-treatment ...
Fariba Behnamfar, Maryam Nazemi, Behnoosh Mohamadi   +2 more
doaj   +1 more source

Cardiovascular ephrinB2 function is essential for embryonic angiogenesis [PDF]

, 2002
EphrinB2, a transmembrane ligand of EphB receptor tyrosine kinases, is specifically expressed in arteries. In ephrinB2 mutant embryos, there is a complete arrest of angiogenesis.
Anderson, David J., Gerety, Sebastian S.
core  

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source