Results 91 to 100 of about 2,813,214 (314)

The time benefits of young adult home stayers in France and Italy: a new perspective on the transition to adulthood? [PDF]

open access: yes, 2017
This article analyses how two co-residing generations contribute to the housework workload in Italy and France during the early 2000s. It studies the intergenerational exchange of time between young adults and their parents by indirectly comparing the ...
Mencarini, Letizia   +3 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Still Too Fat to Fight [PDF]

open access: yes, 2012
The problem of junk food sold in schools is not just a national health issue. It is a national security issue.Over the past 40 years, obesity rates have more than tripled for children and teens. About 1 in 4 young American adults is now too overweight to
Amy Dawson Taggart   +5 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Rare but heard: using asynchronous virtual focus groups, interviews and roundtable discussions to create a personalised psychological intervention for primary sclerosing cholangitis: a protocol

open access: yesBMJ Open, 2019
Introduction Primary sclerosing cholangitis (PSC) is a rare and chronic disease characterised by inflammation and fibrosis of the liver’s bile ducts.
Martine Walmsley   +4 more
doaj   +1 more source

Increased Bilateral Interactions in Middle-Aged Subjects [PDF]

open access: yes, 2014
A hallmark of the age-related neural reorganization is that old versus young adults execute typical motor tasks by a more diffuse neural activation pattern including stronger ipsilateral activation during unilateral tasks.
Inge eZijdewind   +4 more
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Age and lifecycle patterns driving U.S. migration shifts [PDF]

open access: yes, 2013
Migration—people moving between locations—is now driving much of the demographic change occurring in the United States. In this brief, authors Kenneth Johnson, Richelle Winkler, and Luke Rogers share new research on age-related migration patterns to ...
Johnson, Kenneth M.   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The antisocialisation of children and young people: undermining professionals and colonising everyday life [PDF]

open access: yes, 2010
This paper analyses the changing nature of relationships between adults and young people. Adopting aspects of the work of Frank Furedi, the question of the socialisation of children is addressed.
Waiton, Stuart
core  

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