Results 101 to 110 of about 2,813,214 (314)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Prevalence and patterns of physical activity among medical students in Bangalore, India
Electronic Physician, 2013 Background: Physical activity is one of the leading health indicators. The objective was to study the prevalence and patterns of physical activity among young adults.
Krishnakumar Padmapriya +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Guidelines for library service for young adults
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001 Directrius per a la planificació i avaluació de serveis adreçats a adolescents en biblioteques ...
IFLA. Section of Library for Children and Young Adults
doaj
The Lives of Young Adults Who Have Graduated from Residential Children\u27s Mental Health Programs (FULL REPORT) [PDF]
, 2015 This report presents the results of a research process in which 59 young adults who had received residential mental health treatment in the past were sorted into descriptive profiles based on the information they shared about their lives and personal ...
Cameron, Gary, Frensch, Karen
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The lonely glutamine tree in the middle of the infinite critically ill forest
Critical Care, 2021 Panagiotis Briassoulis +4 more
doaj +1 more source
A Promising Start: Year Up's Initial Impacts on Low-Income Young Adults' Careers [PDF]
, 2011 Year Up, a non-profit organization headquartered in Boston, was founded by a former software entrepreneur in 2000 to provide a year of training and work experience to urban young adults ages 18 to 24.
Anne Roder, Mark Elliott
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source