Results 141 to 150 of about 17,995 (289)

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

Advanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu, Wenjuan Tang, Handan Zhang, Jie Liu, Jiaqi Zhang, Yu Yao, Xiao Fu, Xin Chen, Yanmin Zhang   +8 more
wiley   +1 more source

Initial Mass Functions of Young Stellar Clusters from the Gemini Spectroscopic Survey of Nearby Galaxies. I. Young Massive Clusters in the Antennae Galaxies

The Astronomical Journal
The stellar initial mass function (IMF) is a key parameter to understand the star formation process and the integrated properties of stellar populations in remote galaxies.
Jae-Rim Koo, Hyun-Jeong Kim, Beomdu Lim
doaj   +1 more source

Constraining globular cluster formation through studies of young massive clusters - V. ALMA observations of clusters in the Antennae [PDF]

Some formation scenarios that have been put forward to explain multiple populations within Globular Clusters (GCs) require that the young massive cluster have large reservoirs of cold gas within them, which is necessary to form future generations of ...
Henshaw, JD, Hibbard, JE, Brogan, C, Whitmore, B, Cabrera-Ziri, I, Bastian, N, Larsen, SS, Hollyhead, K, Johnson, K, Longmore, SN, Chandar, R, Davies, B   +11 more
core  

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Massive star clusters detected by JWST as natural birthplaces of intermediate-mass black holes

Astronomy & Astrophysics
The James Webb Space Telescope (JWST) has detected, through gravitational lensing, several young massive star clusters (YMCs), which are considered as relevant building blocks of high-redshift galaxies. In this work, we show how a significant fraction of
Schleicher Dominik R. G., Liempi Matías, Giersz Mirek, Vergara Marcelo C., Flammini Dotti Francesco, Solar Paulo, Escala Andrés, Latif Muhammad A., Reinoso Bastián, Askar Abbas, Schneider Raffaella, Capuzzo-Dolcetta Roberto, Saavedra-Bastidas Jorge, Cuevas Fernando   +13 more
doaj   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

FEAST: JWST Uncovers the Emerging Timescales of Young Star Clusters in M83

The Astrophysical Journal
We present JWST NIRCam observations of the emerging young star clusters (eYSCs) detected in the nearby spiral galaxy M83. The NIRcam mosaic encompasses the nuclear starburst, the bar, and the inner spiral arms.
Alice Knutas, Angela Adamo, Alex Pedrini, Sean T. Linden, Varun Bajaj, Jenna E. Ryon, Benjamin Gregg, Ahmad A. Ali, Eric P. Andersson, Arjan Bik, Giacomo Bortolini, Anne S. M. Buckner, Daniela Calzetti, Ana Duarte-Cabral, Bruce G. Elmegreen, Helena Faustino Vieira, John S. Gallagher, Kathryn Grasha, Kelsey Johnson, Thomas S.-Y. Lai, Drew Lapeer, Matteo Messa, Göran Östlin, Elena Sabbi, Linda J. Smith, Monica Tosi   +25 more
doaj   +1 more source

Enhanced Resistive Switching Uniformity in Tantalum Oxide Memristor Devices via Copper Implantation

Advanced Electronic Materials, EarlyView.
Metal oxide memristor devices typically suffer from uncontrolled forming processes and limited resistive switching uniformity due to the stochastic formation of an oxygen vacancy filament. Improved resistive switching uniformity in Ta2O5 memristor is developed by Cu implantation in the switching oxide.
Shaochuan Chen, Ilia Valov
wiley   +1 more source

3D‐Printable Nanoporous Thermosets via Disulfide‐Based Polymerization‐Induced Microphase Separation

Angewandte Chemie, EarlyView.
α‐Lipoic acid‐derived degradable macro‐chain transfer agents (macroCTAs) with tunable hydrophilicity drive polymerization‐induced microphase separation (PIMS) in photocurable resins. Selective etching via disulfide cleavage then generates interconnected nanoporous thermosets, and compatibility with liquid‐crystal display (LCD) 3D printing enables the ...
Xueheng Dai, Kenny Lee, Yuan Xiu, Nathaniel Corrigan, Kun Zhou, Xichuan Li, Christopher M. Bates, Craig J. Hawker, Cyrille Boyer   +8 more
wiley   +2 more sources