Results 101 to 110 of about 4,772,249 (288)

Consultation with children and young people with experience of domestic abuse on Scottish Government National Domestic Abuse Delivery Group draft proposals : main report [PDF]

open access: yes, 2008
Findings and Conclusions: Major Themes • There was support in principle from young people for all of the proposals • Young people gave careful consideration to the proposals and to how they might operate in practice; they expressed some caution about ...
Grimes, Marian   +4 more
core  

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

Young People, Skills and Cities [PDF]

open access: yes
Young highly educated workers developed in the 70’s and 80’s a preference for working in larger cities. As a consequence highly educated young workers in 1990 were over-represented in cities, in spite of the lower wage premium they earned for working in ...
Giovanni Peri
core  

Barriers to participation in education and training [PDF]

open access: yes, 2010
This study explores the barriers and constraints young people currently face when deciding what to do at the end of their compulsory schooling in Year 11.
Evans, Kelly   +6 more
core  

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

open access: yesAdvanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Impact of mental health comorbidity in children and young adults with inflammatory bowel disease: a UK population-based cohort study

open access: yesBMJ Open
Objective To evaluate the impact of mental health comorbidity in children and young adults with inflammatory bowel disease (IBD).Design Retrospective observational study.Setting Representative population, routinely collected primary care data from the UK
Richard K Russell   +2 more
doaj   +1 more source

‘One big wheel’: young people’s participation in service, design, development and delivery (Sharing our experience, Practitioner-led research 2008-2009; PLR0809/080) [PDF]

open access: yes, 2009
How do professionals and agencies seek the views of young people moving from participation to the implementation of service design and delivery? The research involved six white British young people from the Camborne, Pool and Redruth (CPR) area of ...
James, Natasha
core  

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang   +8 more
wiley   +1 more source

The composition of MDSC-subpopulations PMN-like, M-like, and e-like MDSC is associated with the severity of infectious mononucleosis in pediatric patients

open access: yesFrontiers in Immunology
BackgroundPrimary infection with the Epstein-Barr virus (EBV) in early childhood is often asymptomatic, whereas infection with EBV during adolescence or adulthood may lead to infectious mononucleosis (IM).
Lorenz Mihatsch   +20 more
doaj   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

open access: yesAdvanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang   +6 more
wiley   +1 more source

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