Results 261 to 270 of about 19,727 (296)

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Cellular senescence in human liver under normal aging and cancer. [PDF]

Cell Genom
Karpova A, Li X, Peng CW, Gallant KL, Rapp DR, Alligood DM, Houston AJ, Park A, Targino da Costa ALN, Chou WH, Iglesia MD, Herndon JM, Byrnes K, Naser Al Deen N, Lal P, Fang X, Jayasinghe RG, Blatnik JA, Hawkins WG, Sanford DE, Eagon JC, Leigh N, Doyle MBM, Brunt LM, Chapman WC, Panni RZ, Cullinan DR, Davies SR, Guo J, Wyczalkowski MA, Wendl MC, Zhang H, Martin CA, Warner BW, Chheda MG, Stewart SA, Chen F, Fields RC, Ding L.   +38 more
europepmc   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Preserved mitochondrial ribosomal protein gene expression marks a youthful transcriptional state in Chinese nonagenarians and centenarians. [PDF]

Cell Rep Med
Xiao FH, Wang HT, Zhao L, Li GH, Ma SY, Yang LQ, Wang H, Zhang YX, Li J, Kong QP.   +9 more
europepmc   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Listen to the Patient-She is Telling You the Diagnosis. [PDF]

Ann Fam Med
Kannai R.
europepmc   +1 more source

Evidence for the gravity-driven and magnetically regularized gas flows feeding the massive protostellar cluster in Cepheus A. [PDF]

Sci Adv
Sandhyarani P, Eswaraiah C, Li D, Vázquez-Semadeni E, Gómez GC, Thieme TJ, Samal MR, Wang JW, Lai SP, Chen WP, Ojha DK.   +10 more
europepmc   +1 more source

Protocol for identifying recirculating thymic regulatory T cells and characterizing the role of Eos in their function using scRNA-seq and TCR-seq. [PDF]

STAR Protoc
Xie X, Hill T, Otaizo-Carrasquero F, Zhou X, Shevach EM.   +4 more
europepmc   +1 more source

Spatial-temporal evolution of human-shaped landscapes in guilin (7^th-21^st century) for sustainable urban heritage planning. [PDF]

iScience
Tian M, Ai Y, Chen Z, Arif M.
europepmc   +1 more source

Age- and cell-type-specific effects of histone variant H2BE in the brain. [PDF]

Cell Rep
Louzon S, Feierman ER, Qiu Q, Maroni MJ, Quaye CN, Perez-Tremble R, Wu H, Korb E.   +7 more
europepmc   +1 more source