Results 71 to 80 of about 164,968 (341)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

The Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro, Jean L. Turner, Sara C. Beck, Edwin Alexani, Runa Indrei, Bethany M. Welch, Tunhui Xie   +6 more
doaj   +1 more source

How can young massive clusters reach their present-day sizes?

, 2015
The classic question that how young massive star clusters attain their shapes and sizes, as we find them today, remains to be a challenge. Both observational and computational studies of star-forming massive molecular gas clouds infer that massive ...
Banerjee, Sambaran, Kroupa, Pavel
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

JWST Observations of Starbursts: Massive Star Clusters in the Central Starburst of M82

The Astrophysical Journal Letters
We present a near-infrared (NIR) candidate star cluster catalog for the central kiloparsec of M82 based on new JWST NIRCam images. We identify star cluster candidates using the F250M filter, finding 1357 star cluster candidates with stellar masses >10 ^4
Rebecca C. Levy, Alberto D. Bolatto, Divakara Mayya, Bolivia Cuevas-Otahola, Elizabeth Tarantino, Martha L. Boyer, Leindert A. Boogaard, Torsten Böker, Serena A. Cronin, Daniel A. Dale, Keaton Donaghue, Kimberly L. Emig, Deanne B. Fisher, Simon C. O. Glover, Rodrigo Herrera-Camus, María J. Jiménez-Donaire, Ralf S. Klessen, Laura Lenkić, Adam K. Leroy, Ilse De Looze, David S. Meier, Elisabeth A. C. Mills, Juergen Ott, Mónica Relaño, Sylvain Veilleux, Vicente Villanueva, Fabian Walter, Paul P. van der Werf   +27 more
doaj   +1 more source

Unbound stars hold the key to young star cluster history

Astronomy & Astrophysics, 2023
Aims.Gaia delivers the positions and velocities of stars at an unprecedented precision. Therefore, for star clusters, there exists much higher confidence in whether a specific star is a member of a particular cluster or not. However, membership determination is still especially challenging for young star clusters. At ages 2−10 Myr, the gas is expelled,
Arunima, Arunima, Pfalzner, Susanne, Govind, Amith   +2 more
openaire   +3 more sources

Multiple stellar populations in Magellanic Cloud clusters. III. The first evidence of an extended main sequence turn-off in a young cluster: NGC1856 [PDF]

, 2015
Recent studies have shown that the extended main-sequence turn off (eMSTO) is a common feature of intermediate-age star clusters in the Magellanic Clouds (MCs).
Aparicio, A., Bedin, L. R., Bellini, A., Cassisi, S., Jerjen, H., Marino, A. F., Milone, A. P., Pietrinferni, A., Piotto, G., Rich, R. M.   +9 more
core   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Is Earendel a Star Cluster?: Metal-poor Globular Cluster Progenitors at z ∼ 6

The Astrophysical Journal Letters
The strongly lensed z  ∼ 6 Sunrise galaxy offers an incredible opportunity to investigate star formation in the early Universe on parsec or smaller scales.
Massimo Pascale, Liang Dai, Brenda L. Frye, Aliza G. Beverage   +3 more
doaj   +1 more source

Arp 220: A Post-starburst Galaxy with Little Current Star Formation outside of Its Nuclear Disks

The Astrophysical Journal, 2023
The ultraluminous infrared galaxy Arp 220 is a late-stage merger with several tidal structures in the outskirts and two very compact, dusty nuclei that show evidence for extreme star formation and host at least one active galactic nucleus (AGN).
Rupali Chandar, Miranda Caputo, Sean Linden, Angus Mok, Bradley C. Whitmore, Daniela Calzetti, Debra M. Elmegreen, Janice C. Lee, Leonardo Ubeda, Richard White, David O. Cook   +10 more
doaj   +1 more source