Results 41 to 50 of about 64,773 (262)

Les enjeux de la recherche concernant l’enfance et la famille autochtones

Enfances, Familles, Générations, 2016
This article presents a review of the colonial policies that had devastating consequences on Aboriginal children and families, among which residential schools and the enforcement of youth protection regulations.
Sébastien Grammond, Christiane Guay
doaj  

An Exploratory Typology for Understanding Family-Relationship Issues in Kinship-Care Placements

Societies
Family relationships are a distinctive feature of kinship-care placements, but very few studies have examined how the dynamics of these relationships affect the placement experience.
Amilie Dorval, Sonia Hélie, Marie-Andrée Poirier   +2 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Les contacts parent-enfant suite au placement en famille substitut : liens avec la stabilité du placement

Enfances, Familles, Générations, 2017
Research Framework : Preschool children are less likely to be reunified to their biological parents after being in foster care and generally have more stable foster placement. However, little is known about the factors associated with stable placement in
Karine Poitras, George M. Tarabulsy
doaj  

Paucity and the Need for Value Sensitivity in Dealing with Youth Care: Why legal and youth professionals should take cultural and religious considerations seriously

Utrecht Law Review, 2016
At times when radical Islam, jihadists and honour-related violence are well known examples in courtrooms one would expect that professionals in the field of youth protection are specifically aware of aspects leading to certain behaviour.
Wibo van Rossum, Mariëtte van den Hoven
doaj   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Age at entry into the Dutch child protection system of children of parents with intellectual disability: A case-control study

Child Protection and Practice
Background: It is well established that children of parents with intellectual disability (ID) are disproportionately involved in child protection. It is important to identify the characteristics of their child protection trajectories. Objective: Children
Lianne Bakkum, Carlo Schuengel
doaj   +1 more source

فاعلية خدمات وبرامج وحدة التضامن الاجتماعي بجامعة الفيوم في تحقيق الحماية الاجتماعية للشباب الجامعي [PDF]

Mağallaẗ Kulliyyaẗ Al-H̲idmaẗ Al-Īğtimāʿiyyaẗ Lil Dirāst wa Al-Buḥūṯ Al-Īğtimāʿiyyaẗ
     هدفت الدراسة الحالية الي تحديد مستوي فاعلية برامج وخدمات وحدة التضامن الاجتماعي بجامعة الفيوم في تحقيق الحماية الاجتماعية للشباب الجامعي طبقا لأهدافها المحددة، حيث تنتمي هذه الدراسة الي نمط الدراسات التقويمية ، واعتمدت علي المنهج الوصفي باستخدام ...
اسلام محمد فارس مصطفي
doaj   +1 more source

Why and How the Liberalisation of the Cannabis Market in Germany Should Occur

Wirtschaftsdienst, 2022
This article summarises the arguments in favour of legalising cannabis and makes proposals for the design of the regulatory framework. The main argument for a regulated cannabis market is not the expected tax revenues or the legal jobs that would be ...
Justus Haucap, Leon Knoke
doaj   +1 more source