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Preparation, structure, and in vitro chemical durability of yttrium phosphate microspheres for intra-arterial radiotherapy† [PDF]

Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2011
Chemically durable microspheres containing yttrium and/or phosphorus are useful for intra-arterial radiotherapy. In this study, we attempted to prepare yttrium phosphate (YPO4) microspheres with high chemical durability.
Toshiki Miyazaki, Hiroyasu Kanetaka, Zhixia Li   +2 more
exaly   +4 more sources

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Radioembolization of Liver Tumors With Yttrium-90 Microspheres

Seminars in Nuclear Medicine, 2010
Radioembolization (RE), also termed selective internal radiation therapy (SIRT), has been gradually introduced to the clinical arsenal of cytoreductive modalities in recent years. There is growing evidence for efficiency in liver tumors of various entities, with the most prominent ones being hepatocellular carcinoma, colorectal cancer, and ...
Hojjat, Ahmadzadehfar, Hans-Jürgen, Biersack, Samer, Ezziddin   +2 more
openaire   +2 more sources

Yttrium-90 Microspheres: Radiation Therapy for Unresectable Liver Cancer

Journal of Vascular and Interventional Radiology, 2002
Hepatocellular carcinoma (HCC) constitutes a difficult health challenge because of its poor prognosis and limited treatment options. Most available therapies are used only for palliation. The use of yttrium-90 microspheres is a new intraarterial therapy consisting of beta-irradiating microspheres measuring 20-30 micro m in diameter that can be ...
Riad Salem, Brian I. Carr, Jean-François H Geschwind   +2 more
exaly   +3 more sources

Yttrium-90 microspheres for the treatment of hepatocellular carcinoma

Gastroenterology, 2004
Unresectable hepatocellular carcinoma is extremely difficult to treat. TheraSphere consists of yttrium-90 (a pure beta emitter) microspheres, which are injected into the hepatic arteries. This article reviews the safety and survival of patients with hepatocellular carcinoma who were treated with yttrium-90 microspheres.
Jean Francois H, Geschwind, Riad, Salem, Brian I, Carr, Michael C, Soulen, Kenneth G, Thurston, Kathleen A, Goin, Mark, Van Buskirk, Carol A, Roberts, James E, Goin   +8 more
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Biliary Sequelae following Radioembolization with Yttrium-90 Microspheres

Journal of Vascular and Interventional Radiology, 2008
Yttrium-90 (90Y) radioembolization has emerged as a promising and safe therapeutic modality for patients with hepatocellular carcinoma (HCC) or metastatic liver cancer. The present report describes biliary sequelae following intraarterial 90Y therapy in patients with HCC or liver metastases.All patients were treated with 90Y therapy according to ...
Bassel, Atassi, Affaan K, Bangash, Robert J, Lewandowski, Saad, Ibrahim, Laura, Kulik, Mary F, Mulcahy, Ravi, Murthy, Robert K, Ryu, Kent T, Sato, Frank H, Miller, Reed A, Omary, Riad, Salem   +11 more
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Yttrium-90 microsphere radioembolization in unresectable intrahepatic cholangiocarcinoma

Future Oncology, 2017
Intrahepatic cholangiocarcinoma is increasing in frequency worldwide, but radical surgical treatment is practicable in 30-40% of cases. The median survival without therapy is about 8 months, increased to 12 months in combination with systemic chemotherapy.
Mosconi, Cristina, Cappelli, Alberta, Ascanio, Salvatore, Pettinari, Irene, Modestino, Francesco, Renzulli, Matteo, Galaverni, Maria Cristina, Cucchetti, Alessandro, Gramenzi, Annagiulia, Pettinato, Cinzia, Golfieri, Rita   +10 more
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Yttrium-90 microspheres for the treatment of hepatocellular carcinoma: A review

International Journal of Radiation Oncology*Biology*Physics, 2006
To present a critical review of yttrium-90 (TheraSphere) for the treatment of hepatocellular carcinoma (HCC). Medical literature databases (Medline, Cochrane Library, and CANCERLIT) were searched for available literature concerning the treatment of HCC with TheraSphere. These publications were reviewed for scientific and clinical validity.
Riad, Salem, Russell D, Hunter
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Yttrium 90 Microspheres for the Treatment of Hepatocellular Carcinoma

2012
Yttrium-90 microspheres are radioactive particles which are increasingly being employed for treating patients with unresectable hepatocellular carcinoma (HCC). The procedure is called radioembolization. It involves the injection of micron-sized embolic particles loaded with a radioisotope by use of transarterial techniques.
Khairuddin, Memon, Robert J, Lewandowski, Ahsun, Riaz, Riad, Salem   +3 more
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REGRESSION OF LIVER METASTASES FOLLOWING TREATMENT WITH YTTRIUM-90 MICROSPHERES

Australian and New Zealand Journal of Surgery, 1992
Book reviews in this article:Selective internal radiation (SIR) therapy is a technique developed by our group for concentration of Yttrium‐90 microspheres into liver metastases. The technique involves laparotomy, insertion of the catheter into the hepatic artery, redistribution of liver blood flow with vaso‐active agents and incremental embolization of
B N Gray, M A Burton, J E Anderson
exaly   +3 more sources

Urinary Excretion of Yttrium-90 after Radioembolization with Yttrium-90-Labeled Resin-based Microspheres

Health Physics, 2018
In radioembolic therapy (RET) of hepatic malignancies using yttrium-90 (Y)-labeled resin microspheres, radiation protection is primarily concerned with avoiding contamination by radioactive spheres. However, as Y is bound to the microsphere surface by a potentially reversible ion-exchange process, the aim of this study was to assess the extent of the ...
Großer, Oliver Stephan, Ruf, Juri, Pethe, Annette, Kupitz, Dennis, Wissel, Heiko, Benckert, Christoph, Pech, Maciej, Ricke, Jens, Amthauer, Holger   +8 more
openaire   +3 more sources