Results 61 to 70 of about 4,093,256 (305)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Modified Z-scan techniques for investigations of nonlinear chiroptical effects
, 2004 We present simple modifications of the classic Z-scan technique for the investigations of nonlinear chiroptical effects, i.e. nonlinear circular birefringence and two-photon circular dichroism.
M. SAMOC +5 more
core +1 more source
, 2012 Scan offers an interactive and playful narrative where audience can use their mobile phones to scan a QR barcode located on drawing of a skull where tumour, the interaction takes the audience to the actual MRI 'scan' of her ...
Sellars, Nina
core +1 more source
Z-scan measurement with an astigmatic Gaussian beam [PDF]
Journal of the Optical Society of America B, 2000 Z-scan measurement with a slit instead of a circular aperture is proposed and analyzed for an astigmatic Gaussian beam. This new technique can accurately determine not only the nonlinear refractive index but also the ellipticity and positions of x–y foci of the astigmatic beam.
Huang, Y.-L., Sun, C.-K.
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Results in Physics, 2021 The linear optical and electroluminescence properties of small molecular organic material tris-(8-hydroxyquinoline) aluminum (Alq3) are known and extensively investigated by many studies.
Abdu Saeed, Mir. A.N. Razvi, Numan Salah
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Z-scan confocal method for indirect focus location
AIP Advances, 2017 We present a new technique that we have defined as the z-scan confocal method to determine the location and size of the focal spot in a tightly focused ultrashort laser pulse.
Pablo Castro-Marín +5 more
doaj +1 more source
مجلة بغداد للعلوم, 2023 This article studied some linear and nonlinear optical characteristics of different pH solutions from anthocyanin dye extract at 180 oC from red cabbage. First, the linear spectral characteristics, including absorption and transmittance in the range 400-
Rajaa Nader +2 more
doaj +1 more source